The dawn of mRNA vaccines: The COVID-19 case

R Verbeke, I Lentacker, SC De Smedt… - Journal of Controlled …, 2021 - Elsevier
In less than one year since the outbreak of the COVID-19 pandemic, two mRNA-based
vaccines, BNT162b2 and mRNA-1273, were granted the first historic authorization for …

SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19

A Grifoni, J Sidney, R Vita, B Peters, S Crotty… - Cell host & …, 2021 - cell.com
Over the past year, numerous studies in the peer reviewed and preprint literature have
reported on the virological, epidemiological and clinical characteristics of the coronavirus …

SARS-CoV-2 infection of the oral cavity and saliva

N Huang, P Pérez, T Kato, Y Mikami, K Okuda… - Nature medicine, 2021 - nature.com
Despite signs of infection—including taste loss, dry mouth and mucosal lesions such as
ulcerations, enanthema and macules—the involvement of the oral cavity in coronavirus …

CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer

EM Bange, NA Han, P Wileyto, JY Kim, S Gouma… - Nature medicine, 2021 - nature.com
Patients with cancer have high mortality from coronavirus disease 2019 (COVID-19), and the
immune parameters that dictate clinical outcomes remain unknown. In a cohort of 100 …

SARS-CoV-2-specific antibody and T-cell responses 1 year after infection in people recovered from COVID-19: a longitudinal cohort study

L Guo, G Wang, Y Wang, Q Zhang, L Ren, X Gu… - The Lancet …, 2022 - thelancet.com
Background The memory immune response is crucial for preventing reinfection or reducing
disease severity. However, the robustness and functionality of the humoral and T-cell …

Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments

SJ Yong - Infectious diseases, 2021 - Taylor & Francis
Long COVID or post-COVID-19 syndrome first gained widespread recognition among social
support groups and later in scientific and medical communities. This illness is poorly …

Activation or exhaustion of CD8+ T cells in patients with COVID-19

MS Rha, EC Shin - Cellular & molecular immunology, 2021 - nature.com
In addition to CD4+ T cells and neutralizing antibodies, CD8+ T cells contribute to protective
immune responses against SARS-CoV-2 in patients with coronavirus disease 2019 (COVID …

[HTML][HTML] Lipid nanoparticles for delivery of RNA therapeutics: Current status and the role of in vivo imaging

HN Jung, SY Lee, S Lee, H Youn, HJ Im - Theranostics, 2022 - ncbi.nlm.nih.gov
Lipid nanoparticles (LNPs) have been one of the most successful nano-delivery vehicles
that enable efficient delivery of cytotoxic chemotherapy agents, antibiotics, and nucleic acid …

[HTML][HTML] CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses

KE Lineburg, EJ Grant, S Swaminathan… - Immunity, 2021 - cell.com
Efforts are being made worldwide to understand the immune response to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the coronavirus …

[HTML][HTML] S1-Leitlinie post-COVID/long-COVID

AR Koczulla, T Ankermann, U Behrends, P Berlit… - …, 2021 - thieme-connect.com
Die Deutsche Gesellschaft für Pneumologie hat die AWMFS1-Leitlinie Post-COVID/Long-
COVID initiiert. In einem breiten interdisziplinären Ansatz wurde diese S1-Leitlinie …