Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review

RY Gan, HB Li, ZQ Sui, H Corke - Critical reviews in food science …, 2018 - Taylor & Francis
Green tea is one of the most popular beverages in the world, especially in Asian countries.
Consumption of green tea has been demonstrated to possess many health benefits, which …

Molecular targets of epigallocatechin—Gallate (EGCG): A special focus on signal transduction and cancer

A Negri, V Naponelli, F Rizzi, S Bettuzzi - Nutrients, 2018 - mdpi.com
Green tea is a beverage that is widely consumed worldwide and is believed to exert effects
on different diseases, including cancer. The major components of green tea are catechins, a …

Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement

V Aggarwal, HS Tuli, M Tania, S Srivastava… - Seminars in cancer …, 2022 - Elsevier
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …

Combinatorial epigenetics impact of polyphenols and phytochemicals in cancer prevention and therapy

I Arora, M Sharma, TO Tollefsbol - International journal of molecular …, 2019 - mdpi.com
Polyphenols are potent micronutrients that can be found in large quantities in various food
sources and spices. These compounds, also known as phenolics due to their phenolic …

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

[HTML][HTML] Epigenetics: a new bridge between nutrition and health

SW Choi, S Friso - Advances in nutrition, 2010 - Elsevier
Nutrients can reverse or change epigenetic phenomena such as DNA methylation and
histone modifications, thereby modifying the expression of critical genes associated with …

Cancer chemoprevention by dietary polyphenols: promising role for epigenetics

A Link, F Balaguer, A Goel - Biochemical pharmacology, 2010 - Elsevier
Epigenetics refers to heritable changes that are not encoded in the DNA sequence itself, but
play an important role in the control of gene expression. In mammals, epigenetic …

Epigenetic diet: impact on the epigenome and cancer

TM Hardy, TO Tollefsbol - Epigenomics, 2011 - Future Medicine
A number of bioactive dietary components are of particular interest in the field of epigenetics.
Many of these compounds display anticancer properties and may play a role in cancer …

Histone lysine methylation and demethylation pathways in cancer

RA Varier, HTM Timmers - Biochimica et Biophysica Acta (BBA)-Reviews …, 2011 - Elsevier
The genetic changes leading to the development of human cancer are accompanied by
alterations in the structure and modification status of chromatin, which represent powerful …

Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression

JH Lee, TO Khor, L Shu, ZY Su, F Fuentes… - Pharmacology & …, 2013 - Elsevier
Reactive metabolites from carcinogens and oxidative stress can drive genetic mutations,
genomic instability, neoplastic transformation, and ultimately carcinogenesis. Numerous …