Intracerebral haemorrhage

L Puy, AR Parry-Jones, EC Sandset… - Nature Reviews …, 2023 - nature.com
Intracerebral haemorrhage (ICH) is a dramatic condition caused by the rupture of a cerebral
vessel and the entry of blood into the brain parenchyma. ICH is a major contributor to stroke …

[HTML][HTML] Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease

Y Inoue, F Shue, G Bu, T Kanekiyo - Molecular neurodegeneration, 2023 - Springer
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

A Charidimou, G Boulouis, MP Frosch… - The Lancet …, 2022 - thelancet.com
Background Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease,
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …

[HTML][HTML] The neurovascular unit coming of age: a journey through neurovascular coupling in health and disease

C Iadecola - Neuron, 2017 - cell.com
The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress
Review Group meeting of the National Institute of Neurological Disorders and Stroke …

[HTML][HTML] Vasomotion as a driving force for paravascular clearance in the awake mouse brain

SJ van Veluw, SS Hou, M Calvo-Rodriguez… - Neuron, 2020 - cell.com
Paravascular drainage of solutes, including β-amyloid (Aβ), appears to be an important
process in brain health and diseases such as Alzheimer's disease (AD) and cerebral …

Alzheimer's Disease and Vascular Aging: JACC Focus Seminar

M Cortes-Canteli, C Iadecola - Journal of the American College of …, 2020 - jacc.org
Alzheimer's disease, the leading cause of dementia in the elderly, is a neurodegenerative
condition characterized by accumulation of amyloid plaques and neurofibrillary tangles in …

[HTML][HTML] The neuropathological diagnosis of Alzheimer's disease

MA DeTure, DW Dickson - Molecular neurodegeneration, 2019 - Springer
Alzheimer's disease is a progressive neurodegenerative disease most often associated with
memory deficits and cognitive decline, although less common clinical presentations are …

[HTML][HTML] Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue

M Kollmer, W Close, L Funk, J Rasmussen… - Nature …, 2019 - nature.com
The formation of Aβ amyloid fibrils is a neuropathological hallmark of Alzheimer's disease
and cerebral amyloid angiopathy. However, the structure of Aβ amyloid fibrils from brain …

Cerebral small vessel disease: from a focal to a global perspective

A Ter Telgte, EMC Van Leijsen, K Wiegertjes… - Nature Reviews …, 2018 - nature.com
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …

[HTML][HTML] Neuroinflammation in vascular cognitive impairment and dementia: current evidence, advances, and prospects

Z Tian, X Ji, J Liu - International Journal of Molecular Sciences, 2022 - mdpi.com
Vascular cognitive impairment and dementia (VCID) is a major heterogeneous brain
disease caused by multiple factors, and it is the second most common type of dementia in …