Cognitive impact of COVID-19: looking beyond the short term

S Miners, PG Kehoe, S Love - Alzheimer's research & therapy, 2020 - Springer
COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …

Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System: JACC Review Topic of the Week

A Brojakowska, J Narula, R Shimony… - Journal of the American …, 2020 - jacc.org
Severe acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is
mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation …

A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome

A Khan, C Benthin, B Zeno, TE Albertson, J Boyd… - Critical care, 2017 - Springer
Background Renin-angiotensin system (RAS) signaling and angiotensin-converting enzyme
2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome …

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support–free days in patients hospitalized with COVID-19: a …

S Florescu, D Stanciu, M Zaharia, A Kosa, D Codreanu… - Jama, 2023 - jamanetwork.com
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor
clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin …

Renin–angiotensin–aldosterone system and immunomodulation: a state-of-the-art review

D Laghlam, M Jozwiak, LS Nguyen - Cells, 2021 - mdpi.com
The renin–angiotensin system (RAS) has long been described in the field of cardiovascular
physiology as the main player in blood pressure homeostasis. However, other effects have …

Beta‐adrenergic blockers as a potential treatment for COVID‐19 patients

N Vasanthakumar - BioEssays, 2020 - Wiley Online Library
More than 15 million people have been affected by coronavirus disease 2019 (COVID‐19)
and it has caused 640 016 deaths as of July 26, 2020. Currently, no effective treatment …

Plasma angiotensin II is increased in critical coronavirus disease 2019

RL Camargo, B Bombassaro… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) employs angiotensin-
converting enzyme 2 (ACE2) as its receptor for cell entrance, and studies have suggested …

[HTML][HTML] Angiotensin-converting enzyme gene polymorphism and severe lung injury in patients with coronavirus disease 2019

H Zheng, JJ Cao - The American journal of pathology, 2020 - Elsevier
Coronavirus disease 2019 has markedly varied clinical presentations, with most patients
being asymptomatic or having mild symptoms. However, severe acute respiratory disease …

[HTML][HTML] Multifunctional angiotensin converting enzyme 2, the SARS-CoV-2 entry receptor, and critical appraisal of its role in acute lung injury

M Oz, DE Lorke - Biomedicine & Pharmacotherapy, 2021 - Elsevier
The recent emergence of coronavirus disease-2019 (COVID-19) as a pandemic affecting
millions of individuals has raised great concern throughout the world, and the severe acute …

Classic and nonclassic renin-angiotensin systems in the critically ill

L Bitker, LM Burrell - Critical care clinics, 2019 - criticalcare.theclinics.com
The renin-angiotensin systems (RASs) regulate blood pressure, kidney function, and salt
and water homeostasis. Modulation of RAS is central in the intensive care unit spectrum of …