H Ning, G Liu, L Li, Q Liu, H Huang, Z Xie - Nature Communications, 2023 - nature.com
Artificial RNA translation modulation usually relies on multiple components, such as RNA binding proteins (RBPs) or microRNAs (miRNAs) for off-switches and double-inverter …
Q Zhou, T Li, G Fang, Y Pang, X Wang - Pharmaceuticals, 2023 - mdpi.com
Rheumatoid arthritis is an inflammatory disease, and pyroptosis is a form of death associated with an inflammatory response. Pyroptosis, which occurs in synovial and …
D Sarrio, S Colomo, G Moreno‐Bueno - The FEBS Journal, 2023 - Wiley Online Library
One of the hottest topics in biomedical research is to decipher the functional implications of the Gasdermin (GSDM) protein family in human pathologies. These proteins are the key …
EA Jalink, AW Schonk, RA Boon… - Frontiers in cardiovascular …, 2024 - frontiersin.org
Heart failure with preserved ejection fraction (HFpEF) is the largest unmet clinical need in cardiovascular medicine. Despite decades of research, the treatment option for HFpEF is still …
L Eckhart, H Fischer - Biomolecules, 2024 - mdpi.com
Caspase-5 is a protease that induces inflammation in response to lipopolysaccharide (LPS), a component of the cell envelope of Gram-negative bacteria. The expression level of the …
C Springer, D Humayun, R Skouta - Cancers, 2024 - mdpi.com
Simple Summary Cuproptosis is a recently identified form of cell death induced by imbalanced copper levels. We aimed to explore the mechanism underlying copper-induced …
Z Liu, Y Chen, Y Mei, M Yan, H Liang - Molecules, 2023 - mdpi.com
Diabetic cardiomyopathy (DCM) is a pathophysiological condition triggered by diabetes mellitus (DM), which can lead to heart failure (HF). One of the most important cellular …
X Martiañez-Vendrell, J Bloeme-ter Horst… - Viruses, 2024 - mdpi.com
Human coronavirus 229E (HCoV-229E) is associated with upper respiratory tract infections and generally causes mild respiratory symptoms. HCoV-229E infection can cause cell …
W Liu, S Mao, Y Wang, M Wang, M Li… - Journal of Medicinal …, 2024 - ACS Publications
P2Y14 receptor (P2Y14R) is activated by uridine 5′-diphosphate-glucose, which is involved in many human inflammatory diseases. Based on the molecular docking analysis of …