Early detection of diabetic retinopathy

H Safi, S Safi, A Hafezi-Moghadam… - Survey of ophthalmology, 2018 - Elsevier
Diabetic retinopathy (DR) is a primary cause of visual impairment worldwide. Diabetes
mellitus may be associated with ophthalmoscopically nonvisible neurovascular damage that …

Neurovascular unit in diabetic retinopathy: pathophysiological roles and potential therapeutical targets

S Nian, ACY Lo, Y Mi, K Ren, D Yang - Eye and Vision, 2021 - Springer
Diabetic retinopathy (DR), one of the common complications of diabetes, is the leading
cause of visual loss in working-age individuals in many industrialized countries. It has been …

Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

EH Sohn, HW van Dijk, C Jiao… - Proceedings of the …, 2016 - National Acad Sciences
Diabetic retinopathy (DR) has long been recognized as a microvasculopathy, but retinal
diabetic neuropathy (RDN), characterized by inner retinal neurodegeneration, also occurs in …

Retinal vascular endothelial cell dysfunction and neuroretinal degeneration in diabetic patients

M Mrugacz, A Bryl, K Zorena - Journal of clinical medicine, 2021 - mdpi.com
Diabetes mellitus (DM) has become a vital societal problem as epidemiological studies
demonstrate the increasing incidence of type 1 and type 2 diabetes. Lesions observed in the …

Assessment of neurotrophins and inflammatory mediators in vitreous of patients with diabetic retinopathy

JD Boss, PK Singh, HK Pandya, J Tosi… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: To assess vitreous levels of inflammatory cytokines and neurotrophins (NTs) in
diabetic retinopathy (DR) and elucidate their potential roles. Methods: A prospective study …

Diabetic macular ischaemia-a new therapeutic target?

CMG Cheung, A Fawzi, KYC Teo, H Fukuyama… - Progress in Retinal and …, 2022 - Elsevier
Diabetic macular ischaemia (DMI) is traditionally defined and graded based on the
angiographic evidence of an enlarged and irregular foveal avascular zone. However, these …

[HTML][HTML] Diabetic retinopathy is a neurodegenerative disorder

SK Lynch, MD Abràmoff - Vision research, 2017 - Elsevier
Since 1875, controversy has ensued over whether ocular diabetic complications are
primarily vasculopathic or neuropathic in nature. Here, we discuss the historical context by …

Presence and risk factors for glaucoma in patients with diabetes

BJ Song, LP Aiello, LR Pasquale - Current diabetes reports, 2016 - Springer
Diabetes mellitus represents a growing international public health issue with a near
quadrupling in its worldwide prevalence since 1980. Though it has many known …

Metabolomics in the study of retinal health and disease

I Laíns, M Gantner, S Murinello, JA Lasky-Su… - Progress in retinal and …, 2019 - Elsevier
Metabolomics is the qualitative and quantitative assessment of the metabolites (small
molecules< 1.5 kDa) in body fluids. The metabolites are the downstream of the genetic …

Ophthalmic imaging in diabetic retinopathy: A review

O Nanegrungsunk, D Patikulsila… - Clinical & Experimental …, 2022 - Wiley Online Library
Retinal imaging has been a key tool in the diagnosis, evaluation, management and
documentation of diabetic retinopathy (DR) and diabetic macular oedema (DMO) for many …