Neuroprotective effects of PPARα in retinopathy of type 1 diabetes

EA Pearsall, R Cheng, S Matsuzaki, K Zhou, L Ding… - PloS one, 2019 - journals.plos.org
Diabetic retinopathy (DR) is a common neurovascular complication of type 1 diabetes.
Current therapeutics target neovascularization characteristic of end-stage disease, but are …

Supplementation with a highly concentrated docosahexaenoic acid (DHA) in non-proliferative diabetic retinopathy: A 2-year randomized double-blind placebo …

P Piñas García, FJ Hernández Martínez… - Antioxidants, 2022 - mdpi.com
We assessed the effect of a 2-year supplementation with a highly concentrated
docosahexaenoic acid (DHA) product with antioxidant activity on non-proliferative diabetic …

Insulin Promotes Wound Healing by Inactivating NFkβP50/P65 and Activating Protein and Lipid Biosynthesis and alternating Pro/Anti-inflammatory Cytokines …

P Kaur, D Choudhury - Biomolecular Concepts, 2019 - degruyter.com
Four hundred and twenty-two million people have diabetes due to excess free body glucose
in their body fluids. Diabetes leads to various problems including retinopathy, neuropathy …

Neuroprotective Effects of Citicoline in in Vitro Models of Retinal Neurodegeneration

A Matteucci, M Varano, L Gaddini, C Mallozzi… - International journal of …, 2014 - mdpi.com
In recent years, citicoline has been the object of remarkable interest as a possible
neuroprotectant. The aim of this study was to investigate if citicoline affected cell survival in …

Gut microbiota: A potential therapeutic target for management of diabetic retinopathy?

REA Yempén, R Venzel, MCP Campos, LP de Oliveira… - Life Sciences, 2021 - Elsevier
Diabetic Retinopathy (DR) is one of the main complications of Diabetes Mellitus (DM),
drastically impacting individuals of working age over the years, being one of the main …

[HTML][HTML] Loss of melanopsin-expressing retinal ganglion cells in patients with diabetic retinopathy

EA Obara, J Hannibal, S Heegaard… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: Photo-entrainment of the circadian clock is mediated by melanopsin-expressing
retinal ganglion cells (mRGCs) located in the retina. Patients suffering from diabetic …

Системные факторы риска развития первичной открытоугольной глаукомы

ЕА Егоров, ВП Еричев, АЛ Онищенко… - РМЖ. Клиническая …, 2018 - cyberleninka.ru
Первичная открытоугольная глаукома (ПОУГ)—это заболевание, которое проявляется
на поздних стадиях и в итоге приводит к необратимой потере зрения. Постоянные …

Retinal and corneal neurodegeneration and their association with systemic signs of peripheral neuropathy in type 2 diabetes

J Hafner, M Zadrazil, A Grisold, G Ricken… - American Journal of …, 2020 - Elsevier
Purpose To determine the extent of retinal and corneal neurodegeneration and investigate
the association with intraepidermal neuronal loss and diabetic peripheral neuropathy (DPN) …

Nerve growth factor in diabetic retinopathy: beyond neurons

BA Mysona, AY Shanab, SL Elshaer… - Expert Review of …, 2014 - Taylor & Francis
Diabetic retinopathy (DR), a major ocular complication of diabetes, is a leading cause of
blindness in US working age adults with limited treatments. Neurotrophins (NTs), a family of …

ALDH2 attenuates early-stage STZ-induced aged diabetic rats retinas damage via Sirt1/Nrf2 pathway

M He, P Long, W Yan, T Chen, L Guo, Z Zhang… - Life Sciences, 2018 - Elsevier
Abstract Aims Acetaldehyde dehydrogenase 2 (ALDH2) was reported for its protective
properties on myocardial damage, stroke and neurodegeneration disease, but the effects …