This thesis focused on directing the differentiation of pluripotent stem cells towards
telencephalic lateral ganglionic eminence-like fate. The study aimed at developing …

Neurovascular coupling plays fundamental roles in brain homeostasis and development.
Many neurological disorders are associated with vascular dysfunctions, such as epilepsy …

During development of the telencephalon, neurons and glia (oligodendrocytes and
astrocytes) are sequentially generated in a precise temporal and spatial manner …

The development of the forebrain is dependent on controlled regulation of neural
stem/progenitor cells, since the vast majority of all cells in the forebrain are generated by …

The purpose of this study was to elucidate the role of epigenetic mechanisms for the
regulation of genes associated with axonal regeneration following peripheral sciatic nerve …

Tremendous efforts have been made in the last 15 years to determine how interneuron
heterogeneity becomes established (recently reviewed in [4, 5, 6, 7, 8]). It is now widely …

During development of the neocortex, many diverse projection neuron subtypes are
generated under regulation of cell-extrinsic and cell-intrinsic controls. One broad projection …

Maternal infection during pregnancy is associated with increased risk of both schizophrenia
and autism in offspring. Based on this observation, the maternal immune activation mouse …

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