C-reactive protein (CRP) is a member of the highly conserved pentraxin superfamily of
proteins and is often used in clinical practice as a marker of infection and inflammation …

Antiproteinases such as alpha‐2‐macroglobulin (A2M) play a role in hemostasis. A2M is
highly conserved throughout evolution and is a high molecular weight homo‐tetrameric …

Thromboembolism is a common and deadly consequence of COVID-19 infection for
hospitalized patients. Based on clinical evidence pre-dating the COVID-19 pandemic and …

Interventions Patients were randomized to receive either open-label aspirin (n= 565), a
P2Y12 inhibitor (n= 455), or no antiplatelet therapy (control; n= 529). Interventions were …

There is strong evidence that COVID-19 pathophysiology is mainly driven by a
spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from …

Antiphospholipid syndrome and the coagulopathy of COVID-19 share many
pathophysiologic features, including endotheliopathy, hypercoagulability, and activation of …

[Background] Thrombosis is a characteristic complication in Coronavirus disease 2019
(COVID-19). Since coagulopathy has been observed over the entire clinical course …

vaccine effectiveness in terms of protection against actual infection; instead, effectiveness
was inferred from immunogenicity. Cellular immunity was only studied in 60% of the …

Background Biomarkers and clinical indices have been investigated for predicting mortality
in patients with coronavirus disease (COVID-19). We explored the prognostic utility of …

A proportion of people infected with SARS-CoV-2 develop moderate or severe COVID-19,
with an increased risk of thromboembolic complications. The inflammatory response to …