Astrocytes in functional recovery following central nervous system injuries

QM Alhadidi, GA Bahader, O Arvola… - The Journal of …, 2024 - Wiley Online Library
Astrocytes are increasingly recognised as partaking in complex homeostatic mechanisms
critical for regulating neuronal plasticity following central nervous system (CNS) insults …

Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF‐κB Suppression and NLRP3 …

Y Ran, W Su, F Gao, Z Ding, S Yang… - Oxidative medicine …, 2021 - Wiley Online Library
NLRP3 inflammasome‐mediated pyroptosis is a proinflammatory programmed cell death
pathway, which plays a vital role in functional outcomes after stroke. We previously …

Efficacy and safety of DL-3-n-butylphthalide in the treatment of poststroke cognitive impairment: a systematic review and meta-analysis

X Fan, W Shen, L Wang, Y Zhang - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Poststroke cognitive impairment (PSCI) is a common complication observed
after stroke. Current pharmacologic therapies have no definitive evidence for cognitive …

Toward a more inclusive paradigm: thrombectomy for stroke patients with pre-existing disabilities

RW Regenhardt, MJ Young, MR Etherton… - Journal of …, 2021 - jnis.bmj.com
Background Persons with pre-existing disabilities represent over one-third of acute stroke
presentations, but account for a far smaller proportion of those receiving endovascular …

Symmetric CTA collaterals identify patients with slow-progressing stroke likely to benefit from late thrombectomy

RW Regenhardt, RG González, J He, MH Lev… - Radiology, 2022 - pubs.rsna.org
Background Understanding ischemic core growth rate (IGR) is key in identifying patients
with slow-progressing large vessel occlusion (LVO) stroke who may benefit from delayed …

A review of remote ischemic conditioning as a potential strategy for neural repair poststroke

W Yu, C Ren, X Ji - CNS Neuroscience & Therapeutics, 2023 - Wiley Online Library
Ischemic stroke is one of the major disabling health‐care problem and multiple different
approaches are needed to enhance rehabilitation, in which neural repair is the structural …

COVID-19 and gut injury

S Shen, M Gong, G Wang, K Dua, J Xu, X Xu, G Liu - Nutrients, 2022 - mdpi.com
COVID-19 induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
currently a pandemic and it has led to more than 620 million patients with 6.56 million …

Impairment and compensation in dexterous upper-limb function after stroke. From the direct consequences of pyramidal tract lesions to behavioral involvement of both …

A Roby-Brami, N Jarrasse, R Parry - Frontiers in Human …, 2021 - frontiersin.org
Impairments in dexterous upper limb function are a significant cause of disability following
stroke. While the physiological basis of movement deficits consequent to a lesion in the …

Infarct growth despite endovascular thrombectomy recanalization in large vessel occlusive stroke

RW Regenhardt, MR Etherton, AS Das… - Journal of …, 2021 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE Endovascular thrombectomy (EVT) has
revolutionized large vessel occlusion stroke care. However, not all patients with good …

Association of infarct topography and outcome after endovascular thrombectomy in patients with acute ischemic stroke

RW Regenhardt, AK Bonkhoff, M Bretzner… - Neurology, 2022 - AAN Enterprises
Background and Objectives The care of patients with large vessel occlusion (LVO) stroke
has been revolutionized by endovascular thrombectomy (EVT). While EVT has a large effect …