Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options
D Liu, SY Huang, JH Sun, HC Zhang, QL Cai… - Military Medical …, 2022 - Springer
Sepsis is a common complication of combat injuries and trauma, and is defined as a life-
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …
The immunology of sepsis
T van der Poll, M Shankar-Hari, WJ Wiersinga - Immunity, 2021 - cell.com
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to an infection. This recently implemented definition does not capture the …
response to an infection. This recently implemented definition does not capture the …
Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19)
Coronavirus has emerged as a global health threat due to its accelerated geographic
spread over the last two decades. This article reviews the current state of knowledge …
spread over the last two decades. This article reviews the current state of knowledge …
[HTML][HTML] Immune response in COVID-19: A review
The immune system protects us from viruses and diseases. It produces an antibody to kill
pathogen. This review shows a brief picture about the immune system to protect us from …
pathogen. This review shows a brief picture about the immune system to protect us from …
Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: a single center study of 100 patients in …
P Toniati, S Piva, M Cattalini, E Garrafa, F Regola… - Autoimmunity …, 2020 - Elsevier
A hyperinflammatory syndrome (HIS) may cause a life-threatening acute respiratory distress
syndrome (ARDS) in patients with COVID-19 pneumonia. A prospective series of 100 …
syndrome (ARDS) in patients with COVID-19 pneumonia. A prospective series of 100 …
COVID-19: consider cytokine storm syndromes and immunosuppression
As of March 12, 2020, coronavirus disease 2019 (COVID-19) has been con firmed in 125
048 people worldwide, carrying a mortality of approximately 3· 7%, 1 compared with a …
048 people worldwide, carrying a mortality of approximately 3· 7%, 1 compared with a …
C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis
Background: Patients critically ill with coronavirus disease-2019 (COVID-19) feature
hyperinflammation, and the associated biomarkers may be beneficial for risk stratification …
hyperinflammation, and the associated biomarkers may be beneficial for risk stratification …
Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions
The coronavirus disease-19 pandemic (COVID-19), which appeared in China in December
2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up …
2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up …
Thrombosis in COVID‐19
Thrombotic complications are frequent in COVID‐19 and contribute significantly to mortality
and morbidity. We review several mechanisms of hypercoagulability in sepsis that may be …
and morbidity. We review several mechanisms of hypercoagulability in sepsis that may be …
Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study
Background A subset of patients with COVID-19 develops a hyperinflammatory syndrome
that has similarities with other hyperinflammatory disorders. However, clinical criteria …
that has similarities with other hyperinflammatory disorders. However, clinical criteria …