Long-term outcomes of pediatric infections: from traditional infectious diseases to long Covid

D Buonsenso, LD Gennaro, CD Rose… - Future …, 2022 - Future Medicine
There is limited evidence available on the long-term impact of SARS-CoV-2 infection in
children. In this article, the authors analyze the recent evidence on pediatric long Covid and …

[HTML][HTML] COVID-19-related ARDS: key mechanistic features and treatments

J Selickman, CS Vrettou, SD Mentzelopoulos… - Journal of clinical …, 2022 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome historically
characterized by the presence of severe hypoxemia, high-permeability pulmonary edema …

[HTML][HTML] Persistent lung injury and prothrombotic state in long COVID

M Xiang, H Jing, C Wang, VA Novakovic… - Frontiers in …, 2022 - frontiersin.org
Lung injury may persist during the recovery period of COVID-19 as shown through imaging,
six-minute walk, and lung function tests. The pathophysiological mechanisms leading to …

[HTML][HTML] COVID-19 Vasculitis and vasculopathy-Distinct immunopathology emerging from the close juxtaposition of Type II Pneumocytes and Pulmonary Endothelial …

S Giryes, NL Bragazzi, C Bridgewood… - Seminars in …, 2022 - Springer
Abstract The SARS-CoV-2 virus ACE-2 receptor utilization for cellular entry and the defined
ACE-2 receptor role in cardiovascular medicine hinted at dysregulated endothelial function …

[PDF][PDF] Mycobacterium tuberculosis and SARS-CoV-2 co-infections: The knowns and unknowns

KR Chiok, N Dhar, A Banerjee - Iscience, 2023 - cell.com
Health impacts of Mycobacterium tuberculosis (Mtb) and SARS-CoV-2 co-infections are not
fully understood. Both pathogens modulate host responses and induce immunopathology …

[HTML][HTML] Diffuse alveolar damage patterns reflect the immunological and molecular heterogeneity in fatal COVID-19

JS Erjefält, NSX Costa, J Jönsson, O Cozzolino… - …, 2022 - thelancet.com
Background Severe COVID-19 lung disease exhibits a high degree of spatial and temporal
heterogeneity, with different histological features coexisting within a single individual. It is …

[HTML][HTML] The stereotypic response of the pulmonary vasculature to respiratory viral infections: Findings in mouse models of SARS-CoV-2, influenza A and …

S De Neck, R Penrice-Randal, JJ Clark, P Sharma… - Viruses, 2023 - mdpi.com
The respiratory system is the main target of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the cause of coronavirus disease 19 (COVID-19) where acute respiratory …

[HTML][HTML] Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia

L Ye, Y Gao, SWF Mok, W Liao, Y Wang… - Journal of …, 2024 - Springer
Acute lung injury (ALI) is generally caused by severe respiratory infection and characterized
by overexuberant inflammatory responses and inefficient pathogens-containing, the two …

[HTML][HTML] Lung T cell response in COVID-19

MH Shakiba, I Gemünd, M Beyer… - Frontiers in …, 2023 - frontiersin.org
The COVID-19 pandemic has shown the potentially devastating impact of novel respiratory
infections worldwide. Insightful data obtained in the last years have shed light on the …

[HTML][HTML] Evolution of national guidelines on medicines used to treat COVID-19 in pregnancy in 2020–2022: a scoping review

E Maisonneuve, O de Bruin, G Favre, A Goncé… - Journal of clinical …, 2023 - mdpi.com
The lack of inclusion of pregnant women in clinical trials evaluating the effectiveness of
medicines to treat COVID-19 has made it difficult to establish evidence-based treatment …