[HTML][HTML] Genetics and genomics of SARS-CoV-2: A review of the literature with the special focus on genetic diversity and SARS-CoV-2 genome detection

A Rahimi, A Mirzazadeh, S Tavakolpour - Genomics, 2021 - Elsevier
The outbreak of 2019-novel coronavirus disease (COVID-19), caused by SARS-CoV-2,
started in late 2019; in a short time, it has spread rapidly all over the world. Although some …

Coronaviruses—drug discovery and therapeutic options

A Zumla, JFW Chan, EI Azhar, DSC Hui… - Nature reviews Drug …, 2016 - nature.com
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …

The spike protein of SARS-CoV—a target for vaccine and therapeutic development

L Du, Y He, Y Zhou, S Liu, BJ Zheng… - Nature Reviews …, 2009 - nature.com
Severe acute respiratory syndrome (SARS) is a newly emerging infectious disease caused
by a novel coronavirus, SARS-coronavirus (SARS-CoV). The SARS-CoV spike (S) protein is …

Silencing of SARS‐CoV‐2 with modified siRNA‐peptide dendrimer formulation

M Khaitov, A Nikonova, I Shilovskiy, K Kozhikhova… - Allergy, 2021 - Wiley Online Library
Background First vaccines for prevention of Coronavirus disease 2019 (COVID‐19) are
becoming available but there is a huge and unmet need for specific forms of treatment. In …

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

MJ Vincent, E Bergeron, S Benjannet, BR Erickson… - Virology journal, 2005 - Springer
Background Severe acute respiratory syndrome (SARS) is caused by a newly discovered
coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently …

Middle East respiratory syndrome and severe acute respiratory syndrome: current therapeutic options and potential targets for novel therapies

J Dyall, R Gross, J Kindrachuk, RF Johnson… - Drugs, 2017 - Springer
No specific antivirals are currently available for two emerging infectious diseases, Middle
East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS). A …

Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection

VCC Cheng, SKP Lau, PCY Woo… - Clinical microbiology …, 2007 - Am Soc Microbiol
Before the emergence of severe acute respiratory syndrome (SARS) coronavirus (SARS-
CoV) in 2003, only 12 other animal or human coronaviruses were known. The discovery of …

Severe acute respiratory syndrome

JSM Peiris, Y Guan, KY Yuen - Nature medicine, 2004 - nature.com
Severe acute respiratory syndrome (SARS) was caused by a previously unrecognized
animal coronavirus that exploited opportunities provided by'wet markets' in southern China …

The epigenetic implication in coronavirus infection and therapy

S Atlante, A Mongelli, V Barbi, F Martelli, A Farsetti… - Clinical …, 2020 - Springer
Epigenetics is a relatively new field of science that studies the genetic and non-genetic
aspects related to heritable phenotypic changes, frequently caused by environmental and …

Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque

B Li, Q Tang, D Cheng, C Qin, FY Xie, Q Wei, J Xu… - Nature medicine, 2005 - nature.com
Abstract Development of therapeutic agents for severe acute respiratory syndrome (SARS)
viral infection using short interfering RNA (siRNA) inhibitors exemplifies a powerful new …