[HTML][HTML] Coronavirus biology and replication: implications for SARS-CoV-2
P V'kovski, A Kratzel, S Steiner, H Stalder… - Nature Reviews …, 2021 - nature.com
The SARS-CoV-2 pandemic and its unprecedented global societal and economic disruptive
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …
[HTML][HTML] T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
Coronavirus Disease 2019 (COVID-19), has caused a global pandemic, and safe, effective …
Coronavirus Disease 2019 (COVID-19), has caused a global pandemic, and safe, effective …
[HTML][HTML] COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses
U Sahin, A Muik, E Derhovanessian, I Vogler, LM Kranz… - Nature, 2020 - nature.com
An effective vaccine is needed to halt the spread of the severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) pandemic. Recently, we reported safety, tolerability and …
coronavirus-2 (SARS-CoV-2) pandemic. Recently, we reported safety, tolerability and …
[HTML][HTML] What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …
Immunity, endothelial injury and complement-induced coagulopathy in COVID-19
In December 2019, a novel coronavirus was isolated from the respiratory epithelium of
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …
COVID-19 vaccines: The status and perspectives in delivery points of view
Due to the high prevalence and long incubation periods often without symptoms, the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
A dynamic COVID-19 immune signature includes associations with poor prognosis
Improved understanding and management of COVID-19, a potentially life-threatening
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …
The COVID-19 pandemic: a global health crisis
CA Pollard, MP Morran… - Physiological …, 2020 - journals.physiology.org
The novel coronavirus SARS-CoV-2 was identified as the causative agent for a series of
atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019 …
atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019 …
SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway
The pathogenesis of COVID-19 is associated with a hyperinflammatory response; however,
the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here …
the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here …
Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approaches
Y Jin, W Ji, H Yang, S Chen, W Zhang… - Signal transduction and …, 2020 - nature.com
On 12 March 2020, the outbreak of coronavirus disease 2019 (COVID-19) was declared a
pandemic by the World Health Organization. As of 4 August 2020, more than 18 million …
pandemic by the World Health Organization. As of 4 August 2020, more than 18 million …