COVID-19 in 7780 pediatric patients: a systematic review

A Hoang, K Chorath, A Moreira, M Evans… - …, 2020 - thelancet.com
Background Studies summarizing the clinical picture of COVID-19 in children are lacking.
This review characterizes clinical symptoms, laboratory, and imaging findings, as well as …

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …

[HTML][HTML] Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19

YK Yeoh, T Zuo, GCY Lui, F Zhang, Q Liu, AYL Li… - Gut, 2021 - gut.bmj.com
Objective Although COVID-19 is primarily a respiratory illness, there is mounting evidence
suggesting that the GI tract is involved in this disease. We investigated whether the gut …

Considering how biological sex impacts immune responses and COVID-19 outcomes

EP Scully, J Haverfield, RL Ursin… - Nature Reviews …, 2020 - nature.com
A male bias in mortality has emerged in the COVID-19 pandemic, which is consistent with
the pathogenesis of other viral infections. Biological sex differences may manifest …

6-month consequences of COVID-19 in patients discharged from hospital: a cohort study

C Huang, L Huang, Y Wang, X Li, L Ren, X Gu, L Kang… - The Lancet, 2023 - thelancet.com
Background The long-term health consequences of COVID-19 remain largely unclear. The
aim of this study was to describe the long-term health consequences of patients with COVID …

Mucosal immunity in COVID-19: a neglected but critical aspect of SARS-CoV-2 infection

MW Russell, Z Moldoveanu, PL Ogra… - Frontiers in …, 2020 - frontiersin.org
The mucosal immune system is the largest component of the entire immune system, having
evolved to provide protection at the main sites of infectious threat: the mucosae. As SARS …

Antibody response to SARS-CoV-2 infection in humans: A systematic review

N Post, D Eddy, C Huntley, MCI Van Schalkwyk… - PloS one, 2020 - journals.plos.org
Background Progress in characterising the humoral immune response to Severe Acute
Respiratory Syndrome 2 (SARS-CoV-2) has been rapid but areas of uncertainty persist …

Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence

GE Hartley, ESJ Edwards, PM Aui, N Varese… - Science …, 2020 - science.org
Lasting immunity following SARS-CoV-2 infection is questioned because serum antibodies
decline in convalescence. However, functional immunity is mediated by long-lived memory T …

[HTML][HTML] Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

B Krämer, R Knoll, L Bonaguro, M ToVinh, J Raabe… - Immunity, 2021 - cell.com
Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease …

Humoral immune response to SARS-CoV-2 in Iceland

DF Gudbjartsson, GL Norddahl, P Melsted… - … England Journal of …, 2020 - Mass Medical Soc
Background Little is known about the nature and durability of the humoral immune response
to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods …