Lectin pathway mediates complement activation by SARS-CoV-2 proteins
Early and persistent activation of complement is considered to play a key role in the
pathogenesis of COVID-19. Complement activation products orchestrate a proinflammatory …
pathogenesis of COVID-19. Complement activation products orchestrate a proinflammatory …
Peripheral and lung resident memory T cell responses against SARS-CoV-2
J Grau-Expósito, N Sánchez-Gaona, N Massana… - Nature …, 2021 - nature.com
Resident memory T cells (TRM) positioned within the respiratory tract are probably required
to limit SARS-CoV-2 spread and COVID-19. Importantly, TRM are mostly non-recirculating …
to limit SARS-CoV-2 spread and COVID-19. Importantly, TRM are mostly non-recirculating …
Uncontrolled innate and impaired adaptive immune responses in patients with COVID-19 acute respiratory distress syndrome
S Hue, A Beldi-Ferchiou, I Bendib… - American journal of …, 2020 - atsjournals.org
Rationale: Uncontrolled inflammatory innate response and impaired adaptive immune
response are associated with clinical severity in patients with coronavirus disease (COVID …
response are associated with clinical severity in patients with coronavirus disease (COVID …
[HTML][HTML] COVID-19 and the human innate immune system
JL Schultze, AC Aschenbrenner - Cell, 2021 - cell.com
The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the
human population represents a tremendous medical and economic crisis. Innate immunity …
human population represents a tremendous medical and economic crisis. Innate immunity …
Two distinct immunopathological profiles in autopsy lungs of COVID-19
Abstract Coronavirus Disease 19 (COVID-19) is a respiratory disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has grown to a worldwide …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has grown to a worldwide …
COVID-19 and the role of cytokines in this disease
A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study
Objectives The impact of inflammatory rheumatic diseases on COVID-19 severity is poorly
known. Here, we compare the outcomes of a cohort of patients with rheumatic diseases with …
known. Here, we compare the outcomes of a cohort of patients with rheumatic diseases with …
[HTML][HTML] Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels
T cells are involved in the early identification and clearance of viral infections and also
support the development of antibodies by B cells. This central role for T cells makes them a …
support the development of antibodies by B cells. This central role for T cells makes them a …
SARS-CoV-2 triggering autoimmune diseases
L Mobasheri, MH Nasirpour, E Masoumi… - Cytokine, 2022 - Elsevier
Autoimmunity, hyperstimulation of the immune system, can be caused by a variety of
reasons. Viruses are thought to be important environmental elements that contribute to the …
reasons. Viruses are thought to be important environmental elements that contribute to the …
Factors associated with adverse COVID-19 outcomes in patients with psoriasis—insights from a global registry–based study
Background The multimorbid burden and use of systemic immunosuppressants in people
with psoriasis may confer greater risk of adverse outcomes of coronavirus disease 2019 …
with psoriasis may confer greater risk of adverse outcomes of coronavirus disease 2019 …