One of the most important characteristics of the brain compared to other organs is its
elevated metabolic demand. Consequently, neurons consume high quantities of oxygen …

The genetic basis of many epilepsies is increasingly understood, giving rise to the possibility
of precision treatments tailored to specific genetic etiologies. Despite this, current medical …

The pharmacological armamentarium against epilepsy has expanded considerably over the
last three decades, and currently includes over 30 different antiseizure medications. Despite …

Nonviral nanoparticles have emerged as an attractive alternative to viral vectors for gene
therapy applications, utilizing a range of lipid‐based, polymeric, and inorganic materials …

Epilepsy is a long-term neurological condition that results in recurrent seizures.
Approximately 30% of patients with epilepsy have drug-resistant epilepsy (DRE). The …

Objective “How many epilepsy genes are there?” is a frequently asked question. We sought
to (1) provide a curated list of genes that cause monogenic epilepsies, and (2) compare and …

Zingiber officinale is one of the most frequently used medicinal herbs in Asia. Using rodent
seizure models, it was previously shown that Zingiber officinale hydroethanolic extract exerts …

Exosomes are a subset of extracellular vesicles that act as messengers to facilitate
communication between cells. Non-coding RNAs, proteins, lipids, and microRNAs are …

Epilepsy is one of the most common chronic diseases of the central nervous system (CNS).
Treatment of epilepsy remains, however, a clinical challenge with over 30% of patients not …

Epilepsy, a heterogeneous group of brain-related diseases, has continued to significantly
burden society and families. Epilepsy comorbid with neurodevelopmental disorders (NDDs) …