Studies of psychiatric disorders have traditionally focused on emotional symptoms such as
depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are …

Cortical gray matter deficits have been found in patients with schizophrenia, with evidence of
progression over time. The aim of this study was to determine the extent of progressive …

Handedness and brain asymmetry are widely regarded as unique to humans, and
associated with complementary functions such as a left-brain specialization for language …

Context It is unknown how genetic variants conferring liability to psychiatric disorders survive
in the population despite strong negative selection. However, this is key to understanding …

BackgroundThere is a long-standing belief that creativity is coupled with psychopathology.
AimsTo test this alleged association and to investigate whether any such association is the …

We previously demonstrated that patients with schizophrenia or bipolar disorder and their
relatives are overrepresented in creative occupations. Here, we use a new dataset with a …

Cadherins mediate cell–cell adhesion but are also involved in intracellular signaling
pathways associated with neuropsychiatric disease. Most of the∼ 100 cadherins that are …

Diagnostic systems, phenotype models, and theories of etiology incorporate propositions on
the underlying nature of psychosis and schizophrenia phenotypes. These propositions …

Understanding the evolutionary origins of behaviour is a central aim in the study of biology
and may lead to insights into human disorders. Synaptic transmission is observed in a wide …

It has been suggested that the evolution of language might be “the hardest problem in
science”(Christiansen & Kirby, 2003, p. 1). Part of the difficulty is that language has long …