Highlights•Aspergillus and Ustilago produce itaconic acid by very different pathways.•
Transporters play a central role in fungal organic acid production.•Recent discoveries …

The emergence of widespread multidrug resistance (MDR) is a serious challenge for
therapeutics, food-preservation and crop protection. Frequently, MDR is a result of the action …

Metabolic adaptation, and in particular the modulation of carbon assimilatory pathways
during disease progression, is thought to contribute to the pathogenicity of Candida …

Infections caused by opportunistic fungal pathogens have reached concerning numbers due
to the increase of the immunocrompromised human population and to the development of …

The emerging transdisciplinary field of Toxicogenomics aims to study the cell response to a
given toxicant at the genome, transcriptome, proteome, and metabolome levels. This …

We report results on the functional analysis of Saccharomyces cerevisiae ORF YNL065w,
predicted to code for a protein belonging to the poorly characterized major facilitator …

The available genomic sequences of five closely related hemiascomycetous yeast species
(Kluyveromyces lactis, Kluyveromyces waltii, Candida glabrata, Ashbya (Eremothecium) …

Excretion of amino acids by yeast cells was reported long ago but has not been
characterized in molecular terms. It is typically favored by overproduction of the amino acid …

The QDR (quinidine drug resistance) family of genes encodes transporters belonging to the
MFS (major facilitator superfamily) of proteins. We show that QDR transporters, which are …

The de novo formation of multilayered spore walls inside a diploid mother cell is a major
landmark of sporulation in the yeast Saccharomyces cerevisiae. Synthesis of the dityrosine …