[PDF][PDF] Novel insight into RNA modifications in tumour immunity: Promising targets to prevent tumour immune escape

Y Kong, J Yu, S Ge, X Fan - The Innovation, 2023 - cell.com
An immunosuppressive state is a typical feature of the tumour microenvironment. Despite
the dramatic success of immune checkpoint inhibitor (ICI) therapy in preventing tumour cell …

m6A-Atlas v2.0: updated resources for unraveling the N6-methyladenosine (m6A) epitranscriptome among multiple species

Z Liang, H Ye, J Ma, Z Wei, Y Wang… - Nucleic Acids …, 2024 - academic.oup.com
Abstract N 6-Methyladenosine (m6A) is one of the most abundant internal chemical
modifications on eukaryote mRNA and is involved in numerous essential molecular …

[HTML][HTML] m7GHub V2.0: an updated database for decoding the N7-methylguanosine (m7G) epitranscriptome

X Wang, Y Zhang, K Chen, Z Liang, J Ma… - Nucleic Acids …, 2024 - academic.oup.com
With recent progress in mapping N7-methylguanosine (m7G) RNA methylation sites, tens of
thousands of experimentally validated m7G sites have been discovered in various species …

Evaluation of epitranscriptome-wide N6-methyladenosine differential analysis methods

D Duan, W Tang, R Wang, Z Guo… - Briefings in …, 2023 - academic.oup.com
RNA methylation has emerged recently as an active research domain to study post-
transcriptional alteration in gene expression regulation. Various types of RNA methylation …

XGBoost framework with feature selection for the prediction of RNA N5-methylcytosine sites

Z Abbas, M ur Rehman, H Tayara, Q Zou, KT Chong - Molecular Therapy, 2023 - cell.com
5-methylcytosine (m5C) is indeed a critical post-transcriptional alteration that is widely
present in various kinds of RNAs and is crucial to the fundamental biological processes. By …

[HTML][HTML] Combined signature of N7-methylguanosine regulators with their related genes and the tumor microenvironment: a prognostic and therapeutic biomarker for …

T Li, Z Chen, Z Wang, J Lu, D Chen - Frontiers in Immunology, 2023 - frontiersin.org
Background Identifying predictive markers for breast cancer (BC) prognosis and
immunotherapeutic responses remains challenging. Recent findings indicate that N7 …

[HTML][HTML] Evaluation and development of deep neural networks for RNA 5-methyluridine classifications using autoBioSeqpy

L Yu, Y Zhang, L Xue, F Liu, R Jing, J Luo - Frontiers in Microbiology, 2023 - frontiersin.org
Post-transcriptionally RNA modifications, also known as the epitranscriptome, play crucial
roles in the regulation of gene expression during development. Recently, deep learning (DL) …

[HTML][HTML] The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections

DR Ribeiro, A Nunes, D Ribeiro, AR Soares - Frontiers in Genetics, 2023 - frontiersin.org
Emerging evidence highlights the multifaceted roles of the RNA epitranscriptome during
viral infections. By modulating the modification landscape of viral and host RNAs, viruses …

The 2023 Nucleic Acids Research Database Issue and the online molecular biology database collection

DJ Rigden, XM Fernández - Nucleic Acids Research, 2023 - academic.oup.com
Abstract The 2023 Nucleic Acids Research Database Issue contains 178 papers ranging
across biology and related fields. There are 90 papers reporting on new databases and 82 …

[HTML][HTML] m5U-GEPred: prediction of RNA 5-methyluridine sites based on sequence-derived and graph embedding features

Z Xu, X Wang, J Meng, L Zhang, B Song - Frontiers in microbiology, 2023 - frontiersin.org
5-Methyluridine (m 5 U) is one of the most common post-transcriptional RNA modifications,
which is involved in a variety of important biological processes and disease development …