Mexican antidiabetic herbs: valuable sources of inhibitors of α-glucosidases

R Mata, S Cristians, S Escandón-Rivera… - Journal of Natural …, 2013 - ACS Publications
Type II-diabetes mellitus (TII-DM) has been regarded as one of the most important public
health problems in all nations in the 21st century. Although allopathic therapies remain the …

Chemistry and biology of selected Mexican medicinal plants

R Mata, M Figueroa, A Navarrete… - Progress in the Chemistry …, 2019 - Springer
Herbal medicines are an integral element of alternative medical care in Mexico, and the best
testimony to their efficacy and cultural value is their persistence in contemporary Mexican …

Plants of the Rubiaceae Family with Effect on Metabolic Syndrome: Constituents, Pharmacology, and Molecular Targets

F González-Castelazo, LE Soria-Jasso… - Plants, 2023 - mdpi.com
Metabolic syndrome (MetS) predisposes individuals to chronic non-communicable diseases
(NCDs) like type 2 diabetes (T2D), non-alcoholic fatty liver disease, atherosclerosis, and …

Hypoglycemic activity of extracts and compounds from the leaves of Hintonia standleyana and H. latiflora: potential alternatives to the use of the stem bark of these …

S Cristians, JA Guerrero-Analco… - Journal of Natural …, 2009 - ACS Publications
The CH2Cl2− MeOH (1: 1) extract of the leaves of Hintonia standleyana and H. latiflora
caused significant decrease in blood glucose levels in both normal and streptozotozin (STZ) …

Gastroprotective effect of Hintonia latiflora and Hintonia standleyana aqueous extracts and compounds

S Cristians, R Bye, A Navarrete, R Mata - Journal of ethnopharmacology, 2013 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: The stem-barks of Hintonia latiflora and
Hintonia standleyana, locally known as “copalchi”, are used for treating several maladies …

Antimalarial efficacy, cytotoxicity, and genotoxicity of methanolic stem bark extract from Hintonia latiflora in a Plasmodium yoelii yoelii lethal murine malaria model

N Rivera, PY López, M Rojas, TI Fortoul… - Parasitology …, 2014 - Springer
Traditional medicines have been used to treat malaria for thousands of years and are the
source of artemisinin and quinine derivatives. With the increasing levels of drug resistance …

Molecular markers associated with chemical analysis: a powerful tool for quality control assessment of Copalchi Medicinal Plant Complex

S Cristians, R Bye, J Nieto-Sotelo - Frontiers in Pharmacology, 2018 - frontiersin.org
The copalchi complex, Hintonia latiflora, H. standleyana, and Exostema caribaeum, is widely
used in Mexico for treating diabetes and gastrointestinal disorders. The first therapeutic use …

Mexican copalchis of the Rubiaceae family: More than a century of pharmacological and chemical investigations

I Rivero-Cruz, S Cristians, B Ovalle-Magallanes… - Phytochemistry …, 2019 - Springer
The term copalchi has been used in the scientific literature to define a group of plants of the
Rubiaceae and Euphorbiaceae families with extremely bitter stem-barks, useful for treating …

A folk remedy for NIDDM: evidence of antihyperglycemic effects of H. latiflora

M Garcia - 2010 - escholarship.org
Multiple experiments using diabetes animal models have demonstrated the
antihyperglycemic properties of several Mexican Copalchi species, mainly Hintonia latiflora …

Development of a HPLC-DAD Method for the Simultaneous Quantification of 5-O-β-D-galactopyranosyl-7-methoxy-3', 4'-dihydroxy-4-phenylcoumarin and its Aglycone …

S Cristians, K Rubio-Carrasco… - Journal of the Mexican …, 2016 - scielo.org.mx
A sensitive and specific HPLC-DAD method was developed and validated for the
simultaneous quantification of 5-O-β-D-galactopyranosyl-7-methoxy-3', 4'-dihydroxy-4 …