Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health

RL Doty - Trends in Molecular Medicine, 2022 - cell.com
Decreased smell function is related to brain health, future mortality, and quality of life. Most
people inflicted with the SARS-CoV-2 virus evidence some measurable smell dysfunction …

Links between COVID-19 and Parkinson's disease/Alzheimer's disease: reciprocal impacts, medical care strategies and underlying mechanisms

P Huang, LY Zhang, YY Tan, SD Chen - Translational Neurodegeneration, 2023 - Springer
The impact of coronavirus disease 2019 (COVID-19) pandemic on patients with
neurodegenerative diseases and the specific neurological manifestations of COVID-19 have …

SARS‐COV‐2 infection and Parkinson's disease: Possible links and perspectives

HM Al‐kuraishy, AI Al‐Gareeb… - Journal of …, 2023 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive
loss of dopaminergic neurons in the substantia nigra. The hallmarks are the presence of …

Long-term sequelae of COVID-19 in experimental mice

MJ Paidas, DS Cosio, S Ali, NS Kenyon… - Molecular …, 2022 - Springer
We recently reported acute COVID-19 symptoms, clinical status, weight loss, multi-organ
pathological changes, and animal death in a murine hepatitis virus-1 (MHV-1) coronavirus …

COVID-19 and Parkinsonism: a critical appraisal

F Cavallieri, V Fioravanti, F Bove, E Del Prete, S Meoni… - Biomolecules, 2022 - mdpi.com
A few cases of parkinsonism linked to COVID-19 infection have been reported so far, raising
the possibility of a post-viral parkinsonian syndrome. The objective of this review is to …

[HTML][HTML] SARS-CoV-2, long COVID, prion disease and neurodegeneration

Y Zhao, VR Jaber, WJ Lukiw - Frontiers in Neuroscience, 2022 - frontiersin.org
On the last day of the year 2019 a novel Betacoronavirus (2019-nCov), now known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and causing the highly …

Cerebrospinal fluid biomarkers in SARS-CoV-2 patients with acute neurological syndromes

H Chaumont, F Kaczorowski, A San-Galli, PP Michel… - Revue …, 2023 - Elsevier
Background and purpose Mechanisms underlying acute brain injury in SARS-CoV-2
patients remain poorly understood. A better characterization of such mechanisms remains …

[HTML][HTML] Neuropathology in COVID-19 autopsies is defined by microglial activation and lesions of the white matter with emphasis in cerebellar and brain stem areas

JA Stein, M Kaes, S Smola… - Frontiers in …, 2023 - frontiersin.org
Introduction This study aimed to investigate microglial and macrophage activation in 17
patients who died in the context of a COVID-19 infection in 2020 and 2021. Methods …

K18-and CAG-hACE2 transgenic mouse models and SARS-CoV-2: implications for neurodegeneration research

S Dedoni, V Avdoshina, C Camoglio, C Siddi, W Fratta… - Molecules, 2022 - mdpi.com
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a
global pandemic that might lead to very serious consequences. Notably, mental status …

Young COVID-19 patients show a higher degree of microglial activation when compared to controls

J Matschke, H Lahann, S Krasemann… - Frontiers in …, 2022 - frontiersin.org
The severe acute respiratory syndrome-corona virus type 2 (SARS-CoV-2) is the cause of
human coronavirus disease 2019 (COVID-19). Since its identification in late 2019 SARS …