Young COVID-19 patients show a higher degree of microglial activation when compared to controls

J Matschke, H Lahann, S Krasemann… - Frontiers in …, 2022 - frontiersin.org
The severe acute respiratory syndrome-corona virus type 2 (SARS-CoV-2) is the cause of
human coronavirus disease 2019 (COVID-19). Since its identification in late 2019 SARS …

Does SARS-CoV-2 affect neurodegenerative disorders? TLR2, a potential receptor for SARS-CoV-2 in the CNS

MP Szabo, M Iba, A Nath, E Masliah… - Experimental & Molecular …, 2022 - nature.com
Abstract The coronavirus (COVID-19) pandemic, caused by severe acute respiratory system
coronavirus 2 (SARS-CoV-2), has created significant challenges for scientists seeking to …

Does the SARS-CoV-2 spike receptor-binding domain hamper the amyloid transformation of alpha-synuclein after all?

Y Stroylova, A Konstantinova, V Stroylov, I Katrukha… - Biomedicines, 2023 - mdpi.com
Interactions of key amyloidogenic proteins with SARS-CoV-2 proteins may be one of the
causes of expanding and delayed post-COVID-19 neurodegenerative processes …

Protein Quality Control Systems and ER Stress as Key Players in SARS-CoV-2-Induced Neurodegeneration

E Gavilán, R Medina-Guzman… - Cells, 2024 - mdpi.com
The COVID-19 pandemic has brought to the forefront the intricate relationship between
SARS-CoV-2 and its impact on neurological complications, including potential links to …

SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson's disease in human dopaminergic neurons and a mouse model

B Lee, HN Choi, YH Che, M Ko, HM Seong, MG Jo… - Cell Reports …, 2024 - cell.com
While an association between Parkinson's disease (PD) and viral infections has been
recognized, the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Repurposing the in-house generated Alzheimer's disease targeting molecules through computational and preliminary in-vitro studies for the management of SARS …

G Singh, J Thomas, S Wadhawa, A Kashyap… - Molecular Diversity, 2023 - Springer
Covid-19 was declared a world pandemic. Recent studies demonstrated that Covid-19
impairs CNS activity by crossing the blood–brain barrier and ensuing cognitive impairment …

Investigating neurological symptoms of infectious diseases like COVID-19 leading to a deeper understanding of neurodegenerative disorders such as Parkinson's …

J Zhang - Frontiers in Neurology, 2022 - frontiersin.org
Apart from common respiratory symptoms, neurological symptoms are prevalent among
patients with COVID-19. Research has shown that infection with SARS-CoV-2 accelerated …

SARS-CoV-2, COVID-19 and Neurodegeneration

L Tönges, S Klebe - Brain Sciences, 2022 - mdpi.com
The COVID-19 pandemic continues to affect many areas of our daily life. In addition to the
immense societal and economic changes, medical care of patients has now been modified …

COVID-19 outcomes in hospitalized Parkinson's disease patients in two pandemic waves in 2020: a nationwide cross-sectional study from Germany

R Scherbaum, D Bartig, D Richter, EH Kwon… - … Research and Practice, 2022 - Springer
Background The individualized clinical and public health management of the COVID-19
pandemic have changed over time, including care of people with PD. The objective was to …

SARS-CoV-2 neuroinvasion, inflammatory neurodegeneration and Alzheimer's disease

Y Zhao, WJ Lukiw - Frontiers in cellular neuroscience, 2022 - frontiersin.org
COVID-19 is a rapid onset, highly transmissible and lethal viral pneumonia caused by the
novel severe acute respiratory syndrome coronavirus SARS-CoV-2. SARS-CoV2 is currently …