Pharmacogenomics of the natriuretic peptide system in heart failure

A Abuzaanona, D Lanfear - Current heart failure reports, 2017 - Springer
Abstract Purpose of Review Heart failure (HF) continues to be a public health burden
despite advances in therapy, and the natriuretic peptide (NP) system is clearly of critical …

Genetic variation in the natriuretic peptide system and heart failure

DE Lanfear - Heart failure reviews, 2010 - Springer
Heart failure (HF) is a modern epidemic and is one of the few cardiovascular diseases which
is increasing in prevalence. The growing importance of the Natriuretic Peptide (NP) system …

Genetic and nongenetic factors influencing pharmacokinetics of B-type natriuretic peptide

DE Lanfear, S Chow, B Padhukasahasram, J Li… - Journal of cardiac …, 2014 - Elsevier
Abstract Background Natriuretic peptides (NPs) represent a critical pathway in heart failure
(HF). However, there is wide individual variability in NP system activity, which could be partly …

Association of genetic variation with gene expression and protein abundance within the natriuretic peptide pathway

DE Lanfear, B Sunkara, J Li, S Rastogi… - Journal of …, 2013 - Springer
The natriuretic peptide (NP) system is a critical physiologic pathway in heart failure with wide
individual variability in functioning. We investigated the genetic component by testing the …

[图书][B] DNA microarray image segmentation using active contours without edges method

S Ni - 2010 - search.proquest.com
The goal of this dissertation is to build a better segmentation method for DNA microarray
image processing. Segmentation is a partitioning process used to separate a spot area from …