[HTML][HTML] Artificial intelligence for COVID-19 drug discovery and vaccine development

A Keshavarzi Arshadi, J Webb, M Salem… - Frontiers in Artificial …, 2020 - frontiersin.org
SARS-COV-2 has roused the scientific community with a call to action to combat the growing
pandemic. At the time of this writing, there are as yet no novel antiviral agents or approved …

Epitope prediction by novel immunoinformatics approach: a state-of-the-art review

E Raoufi, M Hemmati, S Eftekhari, K Khaksaran… - International Journal of …, 2020 - Springer
Immunoinformatics is a science that helps to create significant immunological information
using bioinformatics softwares and applications. One of the most important applications of …

Drug repurposing for coronavirus (COVID-19): in silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes

AD Elmezayen, A Al-Obaidi, AT Şahin… - Journal of Biomolecular …, 2021 - Taylor & Francis
Abstract In December 2019, COVID-19 epidemic was described in Wuhan, China, and the
infection has spread widely affecting hundreds of thousands. Herein, an effort was made to …

An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study

Z Yang, P Bogdan, S Nazarian - Scientific reports, 2021 - nature.com
The rampant spread of COVID-19, an infectious disease caused by SARS-CoV-2, all over
the world has led to over millions of deaths, and devastated the social, financial and political …

Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches

A Safavi, A Kefayat, E Mahdevar, A Abiri… - Vaccine, 2020 - Elsevier
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …

[HTML][HTML] Design of a novel multiple epitope-based vaccine: An immunoinformatics approach to combat SARS-CoV-2 strains

M Naveed, S Tehreem, S Arshad, SA Bukhari… - Journal of infection and …, 2021 - Elsevier
Abstract Background Since the SARS-CoV-2 outbreak in December 2019 in Wuhan, China,
the virus has infected more than 153 million individuals across the world due to its human-to …

An overview of in silico vaccine design against different pathogens and cancer

K Kardani, A Bolhassani, A Namvar - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …

Analysis of the COVID-19 vaccine development process: an exploratory study of accelerating factors and innovative environments

HGT Defendi, L da Silva Madeira… - Journal of Pharmaceutical …, 2021 - Springer
Purpose The pace of the COVID-19 vaccine development process is unprecedented and is
challenging the traditional paradigm of vaccinology science. The main pressure comes from …

Immunoinformatic design of a COVID-19 subunit vaccine using entire structural immunogenic epitopes of SARS-CoV-2

E Behmard, B Soleymani, A Najafi, E Barzegari - Scientific reports, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is an acute pneumonic disease, with no
prophylactic or specific therapeutical solution. Effective and rapid countermeasure against …

Nanotheranostics against COVID-19: From multivalent to immune-targeted materials

P Hassanzadeh - Journal of controlled release, 2020 - Elsevier
Destructive impacts of COVID-19 pandemic worldwide necessitates taking more appropriate
measures for mitigating virus spread and development of the effective theranostic agents. In …