[HTML][HTML] How to use COVID-19 antiviral drugs in patients with chronic kidney disease

A Kale, V Shelke, N Dagar, HJ Anders… - Frontiers in …, 2023 - frontiersin.org
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid),
Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus …

[HTML][HTML] A systematic review and meta-analysis, investigating dose and time of fluvoxamine treatment efficacy for COVID-19 clinical deterioration, death, and Long …

MI Prasanth, DL Wannigama, AM Reiersen… - Scientific Reports, 2024 - nature.com
Abstract There have been 774,075,242 cases of COVID-19 and 7,012,986 deaths worldwide
as of January 2024. In the early stages of the pandemic, there was an urgent need to reduce …

[HTML][HTML] Quantum DFT studies on the drug delivery of favipiravir using pristine and functionalized chitosan nanoparticles

S Ataei, E Nemati-Kande, A Bahrami - Scientific Reports, 2023 - nature.com
Considering the spread of the COVID-19 pandemic, finding new drugs along with the
development of effective drug delivery methods can help in the treatment of this disease. For …

PIONEER trial: favipiravir to treat moderate COVID-19

S Shalhoub - The Lancet Respiratory Medicine, 2023 - thelancet.com
As the COVID-19 pandemic claimed lives across the globe, several randomised clinical
trials were conducted to evaluate the safety and efficacy of investigational and repurposed …

Uncovering Untapped Carboxylic Acid Reductases (CARs) for One-Step Biosynthesis and Diversification of Bioactive Nitrogen-Containing Heterocycles

P Cai, J He, ZM Song, Y Tian, Z Zhong, D Zhang… - ACS …, 2023 - ACS Publications
Nitrogen-containing heterocycles (N-heterocycles) are essential in drug discovery, with a
majority of best-selling small-molecule drugs containing at least one N-heterocycle. Various …

Respiratory virus infections after allogeneic stem cell transplantation: current understanding, knowledge gaps, and recent advances

JL Piñana, A Pérez, P Chorão… - Transplant Infectious …, 2023 - Wiley Online Library
Before the COVID‐19 pandemic, common community‐acquired seasonal respiratory viruses
(CARVs) were a significant threat to the health and well‐being of allogeneic hematopoietic …

Host factors of SARS-CoV-2 in infection, pathogenesis, and long-term effects

Y Zhang, S Chen, Y Tian, X Fu - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
SARS-CoV-2 is the causative virus of the devastating COVID-19 pandemic that results in an
unparalleled global health and economic crisis. Despite unprecedented scientific efforts and …

Adverse drug reactions associated with COVID-19 management

V Chavda, P Dodiya, V Apostolopoulos - … -Schmiedeberg's Archives of …, 2024 - Springer
The emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
outbreak, which causes COVID-19, had a devastating impact on both people's lives and the …

Is tezepelumab the ubiquitous biologic for severe asthma?

R Beasley, AB Chang - The Lancet Respiratory Medicine, 2023 - thelancet.com
Biologic therapies have transformed severe asthma management. 1 The use of these
treatments has been based on the identification of specific phenotypic characteristics, which …

[HTML][HTML] An Update on SARS-CoV-2 Clinical Trial Results—What We Can Learn for the Next Pandemic

BY Arman, J Brun, ML Hill, N Zitzmann… - International Journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has claimed over 7 million lives
worldwide, providing a stark reminder of the importance of pandemic preparedness. Due to …