Coronavirus vaccine development: from SARS and MERS to COVID-19
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of
coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the …
coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the …
[PDF][PDF] Perspectives on monoclonal antibody therapy as potential therapeutic intervention for Coronavirus disease-19 (COVID-19)
B Shanmugaraj, K Siriwattananon… - Asian Pacific journal …, 2020 - apjai-journal.org
Last decade witnessed the outbreak of many life-threatening human pathogens including
Nipah, Ebola, Chikungunya, Zika, Middle East respiratory syndrome coronavirus (MERS …
Nipah, Ebola, Chikungunya, Zika, Middle East respiratory syndrome coronavirus (MERS …
A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2
R Shi, C Shan, X Duan, Z Chen, P Liu, J Song, T Song… - Nature, 2020 - nature.com
An outbreak of coronavirus disease 2019 (COVID-19),–, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread globally. Countermeasures are needed …
syndrome coronavirus 2 (SARS-CoV-2), has spread globally. Countermeasures are needed …
A universal design of betacoronavirus vaccines against COVID-19, MERS, and SARS
L Dai, T Zheng, K Xu, Y Han, L Xu, E Huang, Y An… - Cell, 2020 - cell.com
Vaccines are urgently needed to control the ongoing pandemic COVID-19 and previously
emerging MERS/SARS caused by coronavirus (CoV) infections. The CoV spike receptor …
emerging MERS/SARS caused by coronavirus (CoV) infections. The CoV spike receptor …
[HTML][HTML] Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies
Coronaviruses make use of a large envelope protein called spike (S) to engage host cell
receptors and catalyze membrane fusion. Because of the vital role that these S proteins play …
receptors and catalyze membrane fusion. Because of the vital role that these S proteins play …
From SARS to MERS, thrusting coronaviruses into the spotlight
Z Song, Y Xu, L Bao, L Zhang, P Yu, Y Qu, H Zhu… - viruses, 2019 - mdpi.com
Coronaviruses (CoVs) have formerly been regarded as relatively harmless respiratory
pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused …
pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused …
Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases
RM Meganck, RS Baric - Nature medicine, 2021 - nature.com
The twenty-first century has already recorded more than ten major epidemic or pandemic
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …
Nanotechnology for COVID-19: therapeutics and vaccine research
The current global health threat by the novel coronavirus disease 2019 (COVID-19) requires
an urgent deployment of advanced therapeutic options available. The role of …
an urgent deployment of advanced therapeutic options available. The role of …
Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition
Here we have generated 3D structures of glycoforms of the spike (S) glycoprotein from
SARS-CoV-2, based on reported 3D structures and glycomics data for the protein produced …
SARS-CoV-2, based on reported 3D structures and glycomics data for the protein produced …
CoV-AbDab: the coronavirus antibody database
MIJ Raybould, A Kovaltsuk, C Marks… - Bioinformatics, 2021 - academic.oup.com
Motivation The emergence of a novel strain of betacoronavirus, SARS-CoV-2, has led to a
pandemic that has been associated with over 700 000 deaths as of August 5, 2020 …
pandemic that has been associated with over 700 000 deaths as of August 5, 2020 …