New developments in the biology of fibroblast growth factors

DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Estrogenic endocrine disruptor exposure directly impacts erectile function

SM Cripps, SA Marshall, DM Mattiske… - Communications …, 2024 - nature.com
Erectile dysfunction (ED) is an extremely prevalent condition which significantly impacts
quality of life. The rapid increase of ED in recent decades suggests the existence of …

[HTML][HTML] The anti-androgenic fungicide triticonazole induces region-specific transcriptional changes in the developing rat perineum and phallus

MK Draskau, CL Schwartz, B Evrard, A Lardenois… - Chemosphere, 2022 - Elsevier
Intrauterine exposure to endocrine disrupting chemicals can interfere with male reproductive
development. This can lead to male reproductive disorders such as hypospadias …

Conserved Targets of Isl1 during Hindlimb Initiation and Outgrowth of the External Genitalia

SG Minchey - 2022 - search.proquest.com
Despite the incredible morphological diversity found within vertebrates, embryonic
development is often regulated by shared foundational mechanism maintained from a …