The oral microbiome: Role of key organisms and complex networks in oral health and disease

L Sedghi, V DiMassa, A Harrington… - Periodontology …, 2021 - Wiley Online Library
States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction

VM Holers, MK Demoruelle, KA Kuhn… - Nature Reviews …, 2018 - nature.com
Individuals at high risk of developing seropositive rheumatoid arthritis (RA) can be identified
for translational research and disease prevention studies through the presence of highly …

Periodontal disease, systemic inflammation and the risk of cardiovascular disease

EF Carrizales-Sepúlveda, A Ordaz-Farías… - Heart, Lung and …, 2018 - Elsevier
Periodontal and cardiovascular disease are both major health issues. Poor oral health has
long been associated with the development of systemic diseases, with the typical example …

Applications of nanomaterials in tissue engineering

X Zheng, P Zhang, Z Fu, S Meng, L Dai, H Yang - RSC advances, 2021 - pubs.rsc.org
Recent advancement in nanotechnology has brought prominent benefits in tissue
engineering, which has been used to repair or reconstruct damaged tissues or organs and …

The dormant blood microbiome in chronic, inflammatory diseases

M Potgieter, J Bester, DB Kell… - FEMS microbiology …, 2015 - academic.oup.com
Blood in healthy organisms is seen as a 'sterile'environment: it lacks proliferating microbes.
Dormant or not-immediately-culturable forms are not absent, however, as intracellular …

Linkage of periodontitis and rheumatoid arthritis: current evidence and potential biological interactions

RS de Molon, C Rossa Jr, RM Thurlings… - International journal of …, 2019 - mdpi.com
The association between rheumatoid arthritis (RA) and periodontal disease (PD) has been
the focus of numerous investigations driven by their common pathological features. RA is an …

The periodontal war: microbes and immunity

JL Ebersole, D Dawson III, P Emecen‐Huja… - Periodontology …, 2017 - Wiley Online Library
Maintenance of periodontal health or transition to a periodontal lesion reflects the
continuous and ongoing battle between the vast microbial ecology in the oral cavity and the …

Oral dysbiotic communities and their implications in systemic diseases

P Sudhakara, A Gupta, A Bhardwaj, A Wilson - Dentistry journal, 2018 - mdpi.com
The human body supports the growth of a wide array of microbial communities in various
niches such as the oral cavity, gastro-intestinal and urogenital tracts, and on the surface of …

Complement in the initiation and evolution of rheumatoid arthritis

VM Holers, NK Banda - Frontiers in immunology, 2018 - frontiersin.org
The complement system is a major component of the immune system and plays a central
role in many protective immune processes, including circulating immune complex …

Dysbiosis of oral microbiota during oral squamous cell carcinoma development

P Sarkar, S Malik, S Laha, S Das, S Bunk… - Frontiers in …, 2021 - frontiersin.org
Infection with specific pathogens and alterations in tissue commensal microbial composition
are intricately associated with the development of many human cancers. Likewise, dysbiosis …