Brain imaging in the assessment for epilepsy surgery

JS Duncan, GP Winston, MJ Koepp… - The Lancet …, 2016 - thelancet.com
Brain imaging has a crucial role in the presurgical assessment of patients with epilepsy.
Structural imaging reveals most cerebral lesions underlying focal epilepsy. Advances in MRI …

A neuroradiologist's guide to arterial spin labeling MRI in clinical practice

M Grade, JA Hernandez Tamames, FB Pizzini… - Neuroradiology, 2015 - Springer
Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …

A sensitive and specific nanosensor for monitoring extracellular potassium levels in the brain

J Liu, F Li, Y Wang, L Pan, P Lin, B Zhang… - Nature …, 2020 - nature.com
Extracellular potassium concentration affects the membrane potential of neurons, and, thus,
neuronal activity. Indeed, alterations of potassium levels can be related to neurological …

Along-tract statistics allow for enhanced tractography analysis

JB Colby, L Soderberg, C Lebel, ID Dinov… - Neuroimage, 2012 - Elsevier
Diffusion imaging tractography is a valuable tool for neuroscience researchers because it
allows the generation of individualized virtual dissections of major white matter tracts in the …

[HTML][HTML] Presurgical epilepsy evaluation and epilepsy surgery

C Baumgartner, JP Koren, M Britto-Arias, L Zoche… - …, 2019 - ncbi.nlm.nih.gov
With a prevalence of 0.8 to 1.2%, epilepsy represents one of the most frequent chronic
neurological disorders; 30 to 40% of patients suffer from drug-resistant epilepsy (that is …

Drug-resistant epilepsy and surgery

J Sheng, S Liu, H Qin, B Li… - Current …, 2018 - ingentaconnect.com
Background: Epilepsy is a chronic brain disease that is caused by various factors and
characterized by recurrent, episodic and temporary central nervous system dysfunction …

Pharmacoresistance and the role of surgery in difficult to treat epilepsy

S Wiebe, N Jette - Nature Reviews Neurology, 2012 - nature.com
Pharmacoresistance occurs in up to 30% of patients with epilepsy, and is most commonly
associated with epilepsy of structural or metabolic origin, abnormal findings on brain …

With or without spikes: localization of focal epileptic activity by simultaneous electroencephalography and functional magnetic resonance imaging

F Grouiller, RC Thornton, K Groening, L Spinelli… - Brain, 2011 - academic.oup.com
In patients with medically refractory focal epilepsy who are candidates for epilepsy surgery,
concordant non-invasive neuroimaging data are useful to guide invasive …

Clinical 7 T MRI: Are we there yet? A review about magnetic resonance imaging at ultra-high field

G Barisano, F Sepehrband, S Ma, K Jann… - The British journal of …, 2019 - academic.oup.com
In recent years, ultra-high field MRI (7 T and above) has received more interest for clinical
imaging. Indeed, a number of studies have shown the benefits from the application of this …

The spectrum of structural and functional imaging abnormalities in temporal lobe epilepsy

BC Bernhardt, A Bernasconi, M Liu, SJ Hong… - Annals of …, 2016 - Wiley Online Library
Objective Although most temporal lobe epilepsy (TLE) patients show marked hippocampal
sclerosis (HS) upon pathological examination, 40% present with no significant cell loss but …