[HTML][HTML] Biomarkers in cardiorenal syndrome

G Goffredo, R Barone, V Di Terlizzi, M Correale… - Journal of clinical …, 2021 - mdpi.com
Cardiorenal syndrome is a clinical manifestation of the bidirectional interaction between the
heart and kidney diseases. Over the last years, in patients with cardiovascular diseases …

[HTML][HTML] Cardiorenal syndrome: a literature review

AO Ajibowo, OE Okobi, E Emore, E Soladoye, CG Sike… - Cureus, 2023 - ncbi.nlm.nih.gov
Cardiorenal syndrome (CRS) is a condition characterized by the intricate two-way
relationship between the heart and kidneys, which can lead to acute or chronic dysfunction …

Rare genetic causes of complex kidney and urological diseases

EE Groopman, G Povysil, DB Goldstein… - Nature Reviews …, 2020 - nature.com
Although often considered a single-entity, chronic kidney disease (CKD) comprises many
pathophysiologically distinct disorders that result in persistently abnormal kidney structure …

[HTML][HTML] Hepsin-mediated processing of uromodulin is crucial for salt-sensitivity and thick ascending limb homeostasis

E Olinger, J Lake, S Sheehan, G Schiano, T Takata… - Scientific reports, 2019 - nature.com
Uromodulin is a zona pellucida-type protein essentially produced in the thick ascending limb
(TAL) of the mammalian kidney. It is the most abundant protein in normal urine. Defective …

Prediction of coronary artery disease using urinary proteomics

D Wei, JD Melgarejo, L Van Aelst… - European Journal of …, 2023 - academic.oup.com
Aims Coronary artery disease (CAD) is multifactorial, caused by complex pathophysiology,
and contributes to a high burden of mortality worldwide. Urinary proteomic analyses may …

[HTML][HTML] The immune responses to different Uropathogens call individual interventions for bladder infection

L Li, Y Li, J Yang, X Xie, H Chen - Frontiers in Immunology, 2022 - frontiersin.org
Urinary tract infection (UTI) caused by uropathogens is the most common infectious disease
and significantly affects all aspects of the quality of life of the patients. However …

The UMOD locus: insights into the pathogenesis and prognosis of kidney disease

O Devuyst, C Pattaro - Journal of the American Society of …, 2018 - journals.lww.com
The identification of genetic factors associated with kidney disease has the potential to
provide critical insights into disease mechanisms. Genome-wide association studies have …

Aqueous extract from Equisetum arvense stimulates the secretion of Tamm-Horsfall protein in human urine after oral intake

B Mo, J Sendker, F Herrmann, S Nowak, A Hensel - Phytomedicine, 2022 - Elsevier
Abstract Background Within European traditional phytotherapy, extracts from different herbal
plants are used for prevention and therapy of uncomplicated urinary tract infections and for …

Cryo‐EM structure of native human uromodulin, a zona pellucida module polymer

A Stsiapanava, C Xu, M Brunati… - The EMBO …, 2020 - embopress.org
Assembly of extracellular filaments and matrices mediating fundamental biological
processes such as morphogenesis, hearing, fertilization, and antibacterial defense is driven …

Hepsin: a multifunctional transmembrane serine protease in pathobiology

S Li, L Wang, S Sun, Q Wu - The FEBS Journal, 2021 - Wiley Online Library
Cell membrane‐bound serine proteases are important in the maintenance of physiological
homeostasis. Hepsin is a type II transmembrane serine protease highly expressed in the …