Heterotopic ossification (HO) is a diverse pathologic process, defined as the formation of
extraskeletal bone in muscle and soft tissues. HO can be conceptualized as a tissue repair …

Traumatic brain injury (TBI) is a leading cause of death and disability, and there are currently
no pharmacological treatments known to improve patient outcomes. Unquestionably …

Heterotopic ossification (HO) is a common occurrence after multiple forms of extensive
trauma. These include arthroplasties, traumatic brain and spinal cord injuries, extensive …

Neurogenic heterotopic ossification (NHO) is the formation of ectopic bone generally in
muscles surrounding joints following spinal cord or brain injury. We investigated the …

Neurological heterotopic ossification (NHO) is a debilitating condition where bone forms in
soft tissue, such as muscle surrounding the hip and knee, following an injury to the brain or …

As brain and bone disorders represent major health issues worldwide, substantial clinical
investigations demonstrated a bidirectional crosstalk on several levels, mechanistically …

Neurological heterotopic ossification (NHO) involves the formation of bone in soft tissue
following a neurological condition, of which the most common are brain and spinal cord …

Heterotopic ossification (HO) refers to abnormal formation of mature lamellar bone in soft
tissues without connection to the periosteum, around proximal articulations, knees and …

Heterotopic ossification (HO), or de novo bone formation in soft tissue, is often observed
following traumatic injury. Recent studies suggest that peripheral nerves may play a key …

Background Heterotopic ossification (HO), either acquired (aHO) or hereditary, such as
fibrodysplasia ossificans progressiva (FOP), is a serious condition without effective …