More than the sum of its parts: uncovering emerging effects of microbial interactions in complex communities

P Geesink, J Ter Horst… - FEMS Microbiology …, 2024 - academic.oup.com
Microbial communities are not only shaped by the diversity of microorganisms and their
individual metabolic potential, but also by the vast amount of intra-and interspecies …

Strategies for tailoring functional microbial synthetic communities

J Jing, P Garbeva, JM Raaijmakers… - The ISME …, 2024 - academic.oup.com
Natural ecosystems harbor a huge reservoir of taxonomically diverse microbes that are
important for plant growth and health. The vast diversity of soil microorganisms and their …

Chaotic turnover of rare and abundant species in a strongly interacting model community

E Mallmin, A Traulsen… - Proceedings of the …, 2024 - National Acad Sciences
The composition of ecological communities varies not only between different locations but
also in time. Understanding the fundamental processes that drive species toward rarity or …

[HTML][HTML] Data-driven prediction of colonization outcomes for complex microbial communities

L Wu, XW Wang, Z Tao, T Wang, W Zuo, Y Zeng… - Nature …, 2024 - nature.com
Microbial interactions can lead to different colonization outcomes of exogenous species, be
they pathogenic or beneficial in nature. Predicting the colonization of exogenous species in …

[HTML][HTML] Microbial life in slow and stopped lanes

RM Walker, VC Sanabria, H Youk - Trends in Microbiology, 2023 - cell.com
Microbes in nature often lack nutrients and face extreme or widely fluctuating temperatures,
unlike microbes in growth-optimized settings in laboratories that much of the literature …

[HTML][HTML] Solving polymicrobial puzzles: evolutionary dynamics and future directions

A Srinivasan, A Sajeevan, S Rajaramon… - Frontiers in Cellular …, 2023 - frontiersin.org
Polymicrobial infections include various microorganisms, often necessitating different
treatment methods than a monomicrobial infection. Scientists have been puzzled by the …

[HTML][HTML] An evolution-based framework for describing human gut bacteria

BA Doran, RY Chen, H Giba, V Behera, B Barat… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The human gut microbiome contains many bacterial strains of the same species ('strain-level
variants'). Describing strains in a biologically meaningful way rather than purely …

Statistical design of a synthetic microbiome that clears a multi-drug resistant gut pathogen

R Oliveira, B Pandey, K Lee, M Yousef, RY Chen… - bioRxiv, 2024 - biorxiv.org
Microbiomes perform critical functions across many environments on Earth1, 2, 3. However,
elucidating principles of their design is immensely challenging4, 5, 6, 7. Using a diverse …

Emergent predictability in microbial ecosystems

J Moran, M Tikhonov - bioRxiv, 2024 - biorxiv.org
Microbial ecosystems carry out essential functions for global climate, human health, and
industry. These complex communities exhibit a surprising amount of functionally relevant …

Challenges in quantifying functional redundancy and selection in microbial communities

PY Ho, K Huang - bioRxiv, 2024 - biorxiv.org
Microbiomes can exhibit large variations in species abundances but high reproducibility in
abundances of functional units, an observation often considered evidence for functional …