Circulating biomarkers instead of genotyping to establish metabolizer phenotypes
R Tremmel, U Hofmann, M Haag… - Annual Review of …, 2024 - annualreviews.org
Pharmacogenomics (PGx) enables personalized treatment for the prediction of drug
response and to avoid adverse drug reactions. Currently, PGx mainly relies on the genetic …
response and to avoid adverse drug reactions. Currently, PGx mainly relies on the genetic …
Using population pharmacokinetic analyses of drugs metabolized by CYP2D6 to study the genotype–phenotype translation
T Frederiksen - Basic & Clinical Pharmacology & Toxicology, 2023 - Wiley Online Library
Abstract Cytochrome P450 2D6 (CYP2D6) is an important drug‐metabolizing enzyme
exhibiting extensive interindividual variability predominantly caused by genetic …
exhibiting extensive interindividual variability predominantly caused by genetic …
Does ethnicity impact CYP2D6 genotype–phenotype relationships?
T Frederiksen, J Areberg, E Schmidt… - Clinical and …, 2023 - Wiley Online Library
Polymorphism of the CYP2D6 gene leads to substantial interindividual variability in CYP2D6
enzyme activity. Despite improvements in prediction of CYP2D6 activity based on genotype …
enzyme activity. Despite improvements in prediction of CYP2D6 activity based on genotype …
The thin line between monooxygenases and peroxygenases. P450s, UPOs, MMOs, and LPMOs: A brick to bridge fields of expertise
D Decembrino, D Cannella - Biotechnology Advances, 2024 - Elsevier
Many scientific fields, although driven by similar purposes and dealing with similar
technologies, often appear so isolated and far from each other that even the vocabularies to …
technologies, often appear so isolated and far from each other that even the vocabularies to …
Comparison of brexpiprazole, aripiprazole, and placebo for Japanese major depressive disorder: A systematic review and network meta‐analysis
T Kishi, K Sakuma, T Saito, A Nakagawa… - …, 2024 - Wiley Online Library
Aim This systematic review and frequentist network meta‐analysis used random‐effects
models is conducted to determine whether there are differences in the efficacy, acceptability …
models is conducted to determine whether there are differences in the efficacy, acceptability …
[引用][C] Caracterización del gen CYP2D6 y sus asociaciones clínicas en pacientes con cáncer de mama tratados con Tamoxifeno
G Ramírez Menza - 2024 - Udelar. FC.