As an ancient infectious disease, tuberculosis (TB) is still the leading cause of death from a
single infectious agent worldwide. Latent TB infection (LTBI) has been recognized as the …

Although tuberculosis (TB) remains one of the leading causes of death from an infectious
disease worldwide, the development of vaccines more effective than bacille Calmette …

The Mycobacterium tuberculosis protein kinase K regulates growth adaptation by facilitating
mycobacterial survival in response to a variety of in vitro and in vivo stress conditions. Here …

Treatment of Mycobacterium tuberculosis (Mtb) infections is particularly arduous. One
challenge to effectively treating tuberculosis is that drug efficacy in vivo often fails to match …

Mycobacterium tuberculosis (M. tb), the causative agent of tuberculosis (TB), is a leading
global cause of death from infectious disease. Biofilms are increasingly recognized as a …

Tuberculosis remains a major threat to global public health, with more than 1.5 million
deaths recorded in 2020. Improved interventions against tuberculosis are urgently needed …

Mycobacterium abscessus (Mab), an emerging opportunistic pathogen, predominantly
infects individuals with underlying pulmonary diseases such as cystic fibrosis (CF). Current …

Mycobacterium bovis and other Mycobacterium tuberculosis complex (MTBC) pathogens
that cause domestic animal and wildlife tuberculosis have received considerably less …

The Extracellular function (ECF) sigma factor SigE is one of the best characterized out of the
13 sigma factors encoded in the Mycobacterium tuberculosis chromosome. SigE is required …

Many cells are capable of maintaining viability in a non-dividing state with minimal
metabolism under unfavorable conditions. These are germ cells, adult stem cells, and …