A guide to phylogenetic metrics for conservation, community ecology and macroecology

CM Tucker, MW Cadotte, SB Carvalho… - Biological …, 2017 - Wiley Online Library
The use of phylogenies in ecology is increasingly common and has broadened our
understanding of biological diversity. Ecological sub‐disciplines, particularly conservation …

Functional redundancy-induced stability of gut microbiota subjected to disturbance

A Moya, M Ferrer - Trends in microbiology, 2016 - cell.com
The microbiota should be considered as just another component of the human epigenetic
landscape. Thus, health is also a reflection of the diversity and composition of gut microbiota …

Microbiome differential abundance methods produce different results across 38 datasets

JT Nearing, GM Douglas, MG Hayes… - Nature …, 2022 - nature.com
Identifying differentially abundant microbes is a common goal of microbiome studies.
Multiple methods are used interchangeably for this purpose in the literature. Yet, there are …

Higher fecal short-chain fatty acid levels are associated with gut microbiome dysbiosis, obesity, hypertension and cardiometabolic disease risk factors

J De la Cuesta-Zuluaga, NT Mueller… - Nutrients, 2018 - mdpi.com
Fiber fermentation by gut microbiota yields short-chain fatty acids (SCFAs) that are either
absorbed by the gut or excreted in feces. Studies are conflicting as to whether SCFAs are …

[PDF][PDF] microViz: an R package for microbiome data visualization and statistics

DJM Barnett, ICW Arts, J Penders - Journal of Open Source Software, 2021 - joss.theoj.org
Summary microViz is an R package for the statistical analysis and visualization of microbiota
data. This package extends the functionality of popular microbial ecosystem data analysis R …

Intermittent fasting promotes white adipose browning and decreases obesity by shaping the gut microbiota

G Li, C Xie, S Lu, RG Nichols, Y Tian, L Li, D Patel… - Cell metabolism, 2017 - cell.com
While activation of beige thermogenesis is a promising approach for treatment of obesity-
associated diseases, there are currently no known pharmacological means of inducing …

Ranking the biases: The choice of OTUs vs. ASVs in 16S rRNA amplicon data analysis has stronger effects on diversity measures than rarefaction and OTU identity …

M Chiarello, M McCauley, S Villéger, CR Jackson - PloS one, 2022 - journals.plos.org
Advances in the analysis of amplicon sequence datasets have introduced a methodological
shift in how research teams investigate microbial biodiversity, away from sequence identity …

Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism

P Pathak, C Xie, RG Nichols, JM Ferrell… - …, 2018 - Wiley Online Library
Bile acids activate farnesoid X receptor (FXR) and G protein–coupled bile acid receptor‐1
(aka Takeda G protein–coupled receptor‐5 [TGR5]) to regulate bile acid metabolism and …

A novel sparse compositional technique reveals microbial perturbations

C Martino, JT Morton, CA Marotz, LR Thompson… - …, 2019 - Am Soc Microbiol
The central aims of many host or environmental microbiome studies are to elucidate factors
associated with microbial community compositions and to relate microbial features to …

Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading Akkermansia muciniphila and Several Short-Chain Fatty Acid–Producing Microbiota in …

J De La Cuesta-Zuluaga, NT Mueller… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE Recent studies suggest the beneficial effects of metformin on glucose
metabolism may be microbially mediated. We examined the association of type 2 diabetes …