Design of an optimal combination therapy with broadly neutralizing antibodies to suppress HIV-1
Infusion of broadly neutralizing antibodies (bNAbs) has shown promise as an alternative to
anti-retroviral therapy against HIV. A key challenge is to suppress viral escape, which is …
anti-retroviral therapy against HIV. A key challenge is to suppress viral escape, which is …
Reversions to consensus are positively selected in HIV-1 and bias substitution rate estimates
Abstract Human immunodeficiency virus 1 (HIV-1) is a rapidly evolving virus able to evade
host immunity through rapid adaptation during chronic infection. The HIV-1 group M has …
host immunity through rapid adaptation during chronic infection. The HIV-1 group M has …
Space and genotype-dependent virus distribution during infection progression
N Bessonov, G Bocharov, V Volpert - Mathematics, 2021 - mdpi.com
The paper is devoted to a nonlocal reaction-diffusion equation describing the development
of viral infection in tissue, taking into account virus distribution in the space of genotypes, the …
of viral infection in tissue, taking into account virus distribution in the space of genotypes, the …
Evolutionary dynamics in the virosphere: from HIV-1 to Bacteriophage evolution
V Druelle - 2024 - edoc.unibas.ch
Evolution is a fundamental force shaping all life on Earth. Viruses, the most numerous and
diverse biological entities on the planet, excel in evolution and thrive in many hosts and …
diverse biological entities on the planet, excel in evolution and thrive in many hosts and …
Developing methods to understand intra-host evolution and the effect of antiviral drugs on RNA viruses
WMJ Pang - 2022 - discovery.ucl.ac.uk
Viral infections are common and are particularly problematic in immunocompromised
individuals. However, other than for HIV, Hepatitis B, Hepatitis C, Influenza, and more …
individuals. However, other than for HIV, Hepatitis B, Hepatitis C, Influenza, and more …