Short-chain fatty-acid-producing bacteria: key components of the human gut microbiota

W Fusco, MB Lorenzo, M Cintoni, S Porcari… - Nutrients, 2023 - mdpi.com
Short-chain fatty acids (SCFAs) play a key role in health and disease, as they regulate gut
homeostasis and their deficiency is involved in the pathogenesis of several disorders …

Enhancing intestinal barrier efficiency: A novel metabolic diseases therapy

Y Zhang, X Zhu, X Yu, P Novák, Q Gui, K Yin - Frontiers in Nutrition, 2023 - frontiersin.org
Physiologically, the intestinal barrier plays a crucial role in homeostasis and nutrient
absorption and prevents pathogenic entry, harmful metabolites, and endotoxin absorption …

Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses

M Wang, B Rousseau, K Qiu, G Huang, Y Zhang… - Nature …, 2023 - nature.com
Increasing evidence implicates the tumor microbiota as a factor that can influence cancer
progression. In patients with colorectal cancer (CRC), we found that pre-resection antibiotics …

Multigroup analysis of compositions of microbiomes with covariate adjustments and repeated measures

H Lin, SD Peddada - Nature Methods, 2024 - nature.com
Microbiome differential abundance analysis methods for two groups are well-established in
the literature. However, many microbiome studies involve more than two groups, sometimes …

Faecal microbiome-based machine learning for multi-class disease diagnosis

Q Su, Q Liu, RI Lau, J Zhang, Z Xu, YK Yeoh… - Nature …, 2022 - nature.com
Systemic characterisation of the human faecal microbiome provides the opportunity to
develop non-invasive approaches in the diagnosis of a major human disease. However …

Multi-omics reveal microbial determinants impacting the treatment outcome of antidepressants in major depressive disorder

Y Wang, J Zhou, J Ye, Z Sun, Y He, Y Zhao, S Ren… - Microbiome, 2023 - Springer
Background There is a growing body of evidence suggesting that disturbance of the gut-
brain axis may be one of the potential causes of major depressive disorder (MDD). However …

Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8+ T cells

X Kang, C Liu, Y Ding, Y Ni, F Ji, HCH Lau, L Jiang… - Gut, 2023 - gut.bmj.com
Objective Roseburia intestinalis is a probiotic species that can suppress intestinal
inflammation by producing metabolites. We aimed to study the role of R. intestinalis in …

Dietary Fat Modulation of Gut Microbiota and Impact on Regulatory Pathways Controlling Food Intake

S Hamamah, A Amin, AL Al-Kassir, J Chuang… - Nutrients, 2023 - mdpi.com
Obesity is a multifactorial disease that continues to increase in prevalence worldwide.
Emerging evidence has shown that the development of obesity may be influenced by …

Environmental and human microbiome for health

B Panthee, S Gyawali, P Panthee, K Techato - Life, 2022 - mdpi.com
Microorganisms are an essential part of life on the earth and can exist in association with
virtually any living thing. The environmental microbiome is much more diverse than the …

Gut commensal Kineothrix alysoides mitigates liver dysfunction by restoring lipid metabolism and gut microbial balance

KJ Choi, MY Yoon, JE Kim, SS Yoon - Scientific Reports, 2023 - nature.com
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as Non-
Alcoholic Fatty Liver Disease, is a widespread liver condition characterized by excessive fat …