Multiple functions of p21 in cancer radiotherapy

Y Kuang, J Kang, H Li, B Liu, X Zhao, L Li… - Journal of Cancer …, 2021 - Springer
Background Greater than half of cancer patients experience radiation therapy, for both
radical and palliative objectives. It is well known that researches on radiation response …

125I seeds inhibit proliferation and promote apoptosis in cholangiocarcinoma cells by regulating the AGR2-mediated p38 MAPK pathway

X Zhou, W Zhang, M Dou, Z Li, Z Liu, J Li, C Tian… - Cancer Letters, 2022 - Elsevier
Abstract 125 I seeds can effectively inhibit the growth of a variety of cancer cells. It has been
used in the treatment of a variety of cancers, and has achieved certain curative effect …

Ultrasound-targeted microbubble destruction-mediated inhibition of livin expression accelerates ovarian cancer cell apoptosis

X Xu, S Yu, X Liu, Y Feng, E Zhao - Genetics Research, 2021 - cambridge.org
Objective. Ultrasound-targeted microbubble destruction (UTMD) technique has recently
been developed as a nonviral delivery of gene therapy. This study aimed at investigating the …

Computed tomography-guided iodine-125 radioactive seed implantation in small-cell lung cancer: A retrospective study

M Li, P Liu, H Wang, B Wang, J Zhou, Y Jin… - Journal of …, 2022 - termedia.pl
Purpose Lung cancer is the second most common cancer worldwide [1], and is generally
categorized into small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) …

Activation of M2 macrophage autophagy by rapamycin increases the radiosensitivity of colorectal cancer xenografts

L Shao, Y Wu, J Cao, F Zhong, X Yang… - Journal of Cancer …, 2024 - journals.lww.com
Background: Tumor-associated macrophages (TAMs) are intimately involved in cancer
radiochemotherapy resistance. However, the mechanism by which macrophages affect …

Comparative transcriptome analysis providing inhibitory mechanism of lung cancer A549 cells by radioactive 125I seed

F Liu, J Bao, J Chen, W Song - Journal of Radioanalytical and Nuclear …, 2021 - Springer
In this study, A549 cells treated by radioactive 125 I seed were sequenced using Illumina
HiSeq PE150, and then the transcriptome was analyzed using bioinformatics methods …

Immunohistochemical Analysis of Lung Adenocarcinoma in Russian Mayak Nuclear Workers

GV Sychugov, TV Azizova, GV Zhuntova… - Cancer …, 2023 - Taylor & Francis
Specimens of lung adenocarcinoma (AdCa) from Russian nuclear workers (n= 54) exposed
to alpha particles and gamma rays and from individuals non-exposed to radiation (n= 21) …

上调Decorin 对口腔鳞癌荷瘤裸鼠EGFR, C-Myc, p21 表达的影响

郭梦瑶, 李凯玉, 聂敏海, 刘旭倩 - 上海口腔医学, 2023 - sjos.cn
目的: 探讨饰胶蛋白聚糖基因(decorin, DCN) 过表达对口腔鳞癌(oral squamous cell
carcinoma, OSCC) 裸鼠荷瘤中表皮生长因子受体(epidermal growth factor receptor, EGFR) …

125I seed implantation enhances arsenic trioxide-induced apoptosis and anti-angiogenesis in lung cancer xenograft mice

ZH Chen, YL Zhang, B Yuan, WJ Chen, GY Lei… - Clinical and …, 2023 - Springer
Abstract Background and Purpose Arsenic trioxide (ATO) exerts anticancer effects on lung
cancer. However, the clinical use of ATO is limited due to its systemic toxicity and resistance …

[HTML][HTML] The efficacy and safety of 125I seeds combined with biliary stent placement versus stent placement alone for malignant biliary obstruction: a systematic review …

F Gao, X Huang, Y Wang - Quantitative Imaging in Medicine and …, 2023 - ncbi.nlm.nih.gov
Background Currently, it is unknown whether iodine-125 (125 I) stent implantation has the
same therapeutic effect on patients with malignant biliary obstruction (MBO) caused by …