Alterations in Immune‐Related Defensin Alpha 4 (DEFA4) Gene Expression in Health and Disease

F Basingab, A Alsaiary, S Almontashri… - International Journal …, 2022 - Wiley Online Library
Defensin Alpha 4 (DEFA4) is the fourth member of the Alpha Defensins family known as a
part of antimicrobial peptides in the innate immune system. DEFA4 has a strong preference …

Identification of host transcriptome-guided repurposable drugs for SARS-CoV-1 infections and their validation with SARS-CoV-2 infections by using the integrated …

FF Ahmed, MS Reza, MS Sarker, MS Islam… - PLoS …, 2022 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is one of the most severe
global pandemic due to its high pathogenicity and death rate starting from the end of 2019 …

Network-based analysis of fatal comorbidities of COVID-19 and potential therapeutics

B Chakrabarty, D Das, G Bulusu… - IEEE/ACM transactions …, 2021 - ieeexplore.ieee.org
COVID-19 is a highly contagious disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The case-fatality rate is significantly higher in older patients …

Meta-data analysis to explore the hub of the hub-genes that influence SARS-CoV-2 infections highlighting their pathogenetic processes and drugs repurposing

MP Mosharaf, MK Kibria, MB Hossen, MA Islam… - Vaccines, 2022 - mdpi.com
The pandemic of SARS-CoV-2 infections is a severe threat to human life and the world
economic condition. Although vaccination has reduced the outspread, but still the situation is …

Network Pharmacology and Molecular Docking Elucidate the Underlying Pharmacological Mechanisms of the Herb Houttuynia cordata in Treating Pneumonia …

J Liu, S Yuan, Y Yao, J Wang, G Scalabrino, S Jiang… - Viruses, 2022 - mdpi.com
Used in Asian countries, including China, Japan, and Thailand, Houttuynia cordata Thumb
(H. cordata; Saururaceae, HC) is a traditional herbal medicine that possesses favorable …

An experimental in silico study on COVID‐19: Response of neutrophil‐related genes to antibiotics

SR Mousavi, H Lotfi, S Salmanizadeh… - Health Science …, 2022 - Wiley Online Library
Abstract Background and Aims All components of the immune system are involved in
alleviating severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection …

Classification and severity progression measure of COVID-19 patients using pairs of multi-omic factors

T Chen, P Polak, S Uryasev - Journal of Applied Statistics, 2023 - Taylor & Francis
Early detection and effective treatment of severe COVID-19 patients remain two major
challenges during the current pandemic. Analysis of molecular changes in blood samples of …

[HTML][HTML] Pathway Analysis of Patients with Severe Acute Respiratory Syndrome

A Khaleel, AB Zakariya, M Niazi, NA Qinna… - Drug …, 2022 - thieme-connect.com
Background Coronaviruses are emerging threats for human health, as demonstrated by the
ongoing coronavirus disease 2019 (COVID-19) pandemic that is caused by severe acute …

Classification of COVID19 Patients Using Robust Logistic Regression

A Ghosh, M Jaenada, L Pardo - Journal of Statistical Theory and Practice, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID19) has triggered a global pandemic affecting
millions of people. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing …

Searching Prognostic Hub Genes for the Management of Gliomagenesis through Transcriptome Profiling

P Murali, MK Thirunavukkarasu, P Ramesh… - 2024 - researchsquare.com
Despite the recent advancements in the treatment of gliomagenesis, the disease prognosis
with the current treatment interventions is still awful with a median overall survival of only 15 …