The current landscape of the antimicrobial peptide melittin and its therapeutic potential

HQ Zhang, C Sun, N Xu, W Liu - Frontiers in Immunology, 2024 - frontiersin.org
Melittin, a main component of bee venom, is a cationic amphiphilic peptide with a linear α-
helix structure. It has been reported that melittin can exert pharmacological effects, such as …

Power-series solutions of fractional-order compartmental models

M Jornet - Computational and Applied Mathematics, 2024 - Springer
Compartmental models based on coupled differential equations of fractional order have
been widely employed in the literature for modeling. An abstraction of these models is given …

Eliminating the HIV tissue reservoir: current strategies and challenges

K Li, Q Zhang - Infectious Diseases, 2024 - Taylor & Francis
Background Acquired immunodeficiency syndrome (AIDS) is still one of the most
widespread and harmful infectious diseases in the world. The presence of reservoirs …

Inhibition of Cxcr4 Disrupts Mouse Embryonic Palatal Mesenchymal Cell Migration and Induces Cleft Palate Occurrence

X Zheng, X Zhao, Y Wang, J Chen, X Wang… - International Journal of …, 2023 - mdpi.com
Many processes take place during embryogenesis, and the development of the palate
mainly involves proliferation, migration, osteogenesis, and epithelial–mesenchymal …

HIV infection and ART exposure impact tumor T-cell receptor repertoire of diffuse large B-cell lymphoma

SM Roush, J Coelho, AM Xu, K Puranam… - JCI …, 2024 - Am Soc Clin Investig
The most common subtype of lymphoma globally, diffuse large B-cell lymphoma (DLBCL), is
a leading cause of cancer death in people with HIV (HIV+). The restructuring of the T-cell …

Role of PIN1 in human pathology: Cellular regulation, pathogenesis and therapeutic implications

J Maggio, RG Armando, L Balcone… - World Academy of …, 2023 - spandidos-publications.com
Peptidyl-prolyl isomerase NIMA-interacting 1 (PIN1) plays a crucial regulatory role in cells,
and it is the only enzyme capable of selectively binding to phosphorylated proline-directed …

[HTML][HTML] Amino acid substitution of the membrane-proximal external region alter neutralization sensitivity in a chronic HIV-1 clade B infected patient

Y Fu, S Wang, Y Hao, D Li, L Ren, Z Wang, R Chen… - Virus Research, 2024 - Elsevier
The membrane-proximal external region (MPER) represents a highly conserved region of
the Human Immunodeficiency Virus (HIV) envelope glycoprotein (env) targeted by several …

Evolução histórica da terapia antirretroviral na infecção pelo HIV no Brasil

IC Stacanelli, MLR Maia… - Revista Unimontes …, 2024 - periodicos.unimontes.br

EFEKTIVITAS MENGONSUMSI OBAT ANTIRETROVIRAL DALAM MENURUNKAN ANGKA VIRAL LOAD PADA ODHA

CL Fahrani, R Romadi, A Nuswantoro… - Media Penelitian …, 2023 - jurnal.polkesban.ac.id
Human immunodeficiency virus (HIV) telah menginfeksi banyak orang di seluruh dunia. Di
Indonesia sendiri, sekitar 540.000 orang telah terinfeksi HIV dan hidup dengan acquired …

The role and impact of Nef and Nef inhibitor in HIV-induced impairment of CD4 T-cells

D Mahesh - 2024 - d-scholarship.pitt.edu
This study, utilizing in vitro models, aims to examine the effects of Nef and its inhibitors on
the impairment of CD4 T cells induced by HIV. The primary objectives are to uncover the …