[HTML][HTML] Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes

TPM Scheithauer, E Rampanelli, M Nieuwdorp… - Frontiers in …, 2020 - frontiersin.org
The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D).
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …

Intestinal Cetobacterium and acetate modify glucose homeostasis via parasympathetic activation in zebrafish

A Wang, Z Zhang, Q Ding, Y Yang, J Bindelle… - Gut …, 2021 - Taylor & Francis
The capability of carbohydrate utilization in fish is limited compared to mammals. It has
scientific and practical significance to improve the ability of fish to use carbohydrates. The …

[HTML][HTML] Research progress in the relationship between type 2 diabetes mellitus and intestinal flora

Q Ma, Y Li, P Li, M Wang, J Wang, Z Tang… - Biomedicine & …, 2019 - Elsevier
Type 2 diabetes mellitus (T2DM) is a common clinical chronic disease, while its
pathogenesis is still inconclusive. Intestinal flora, the largest micro-ecological system in the …

Unique roles in health promotion of dietary flavonoids through gut microbiota regulation: Current understanding and future perspectives

Z Li, Z Ren, L Zhao, L Chen, Y Yu, D Wang, X Mao… - Food Chemistry, 2023 - Elsevier
Advances in understanding the biological effects of dietary flavonoids and flavonoid-rich
foods have been reported. Improving knowledge about their beneficial effects, and …

[HTML][HTML] The gut microbiome and sex hormone-related diseases

S He, H Li, Z Yu, F Zhang, S Liang, H Liu… - Frontiers in …, 2021 - frontiersin.org
The role of the gut microbiome has been a hot topic in recent years. One aim of this review is
to shed light on the crosstalk between sex hormones and the gut microbiome. Researchers …

Butyrate to combat obesity and obesity‐associated metabolic disorders: Current status and future implications for therapeutic use

T van Deuren, EE Blaak, EE Canfora - Obesity Reviews, 2022 - Wiley Online Library
Evidence is increasing that disturbances in the gut microbiome may play a significant role in
the etiology of obesity and type 2 diabetes. The short chain fatty acid butyrate, a major end …

[HTML][HTML] Incomplete penetrance and variable expressivity: from clinical studies to population cohorts

R Kingdom, CF Wright - Frontiers in Genetics, 2022 - frontiersin.org
The same genetic variant found in different individuals can cause a range of diverse
phenotypes, from no discernible clinical phenotype to severe disease, even among related …

[HTML][HTML] GWAS, MWAS and mGWAS provide insights into precision agriculture based on genotype-dependent microbial effects in foxtail millet

Y Wang, X Wang, S Sun, C Jin, J Su, J Wei… - Nature …, 2022 - nature.com
Genetic and environmental factors collectively determine plant growth and yield. In the past
20 years, genome-wide association studies (GWAS) have been conducted on crops to …

[HTML][HTML] Role of gut microbiota in the development of insulin resistance and the mechanism underlying polycystic ovary syndrome: a review

F He, Y Li - Journal of ovarian research, 2020 - Springer
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder.
Typically, it is characterized by hirsutism, hyperandrogenism, ovulatory dysfunction …

Genetic risk scores for diabetes diagnosis and precision medicine

MS Udler, MI McCarthy, JC Florez… - Endocrine …, 2019 - academic.oup.com
During the last decade, there have been substantial advances in the identification and
characterization of DNA sequence variants associated with individual predisposition to type …