[HTML][HTML] Gut microbiota: A new target for T2DM prevention and treatment

L Liu, J Zhang, Y Cheng, M Zhu, Z Xiao… - Frontiers in …, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM), one of the fastest growing metabolic diseases, has been
characterized by metabolic disorders including hyperglycemia, hyperlipidemia and insulin …

Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit time

P de Groot, T Scheithauer, GJ Bakker, A Prodan… - Gut, 2020 - gut.bmj.com
Objective Bariatric surgery improves glucose metabolism. Recent data suggest that faecal
microbiota transplantation (FMT) using faeces from postbariatric surgery diet-induced obese …

[HTML][HTML] Beneficial effect of the short-chain fatty acid propionate on vascular calcification through intestinal microbiota remodelling

J Yan, Y Pan, W Shao, C Wang, R Wang, Y He… - Microbiome, 2022 - Springer
Background Vascular calcification is a major cause of the high morbidity and mortality of
cardiovascular diseases and is closely associated with the intestinal microbiota. Short-chain …

[HTML][HTML] Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study

G Ecklu-Mensah, C Choo-Kang, MG Maseng… - Nature …, 2023 - nature.com
The relationship between microbiota, short chain fatty acids (SCFAs), and obesity remains
enigmatic. We employ amplicon sequencing and targeted metabolomics in a large (n …

Intestinal dysbiosis in nonalcoholic fatty liver disease (NAFLD): focusing on the gut–liver axis

H Han, Y Jiang, M Wang, M Melaku, L Liu… - Critical reviews in …, 2023 - Taylor & Francis
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders
in humans, partly because it is closely related to metabolic disorders of the liver with …

[HTML][HTML] Modulatory mechanisms of the NLRP3 inflammasomes in diabetes

S Ding, S Xu, Y Ma, G Liu, H Jang, J Fang - Biomolecules, 2019 - mdpi.com
The inflammasome is a multiprotein complex that acts to enhance inflammatory responses
by promoting the production and secretion of key cytokines. The best-known inflammasome …

Revisiting the role of Akkermansia muciniphila as a therapeutic bacterium

J Si, H Kang, HJ You, GP Ko - Gut Microbes, 2022 - Taylor & Francis
Despite a short history since its first isolation, Akkermansia muciniphila has been extensively
studied in relation to its effects on human metabolism. A recent human intervention study …

[HTML][HTML] The role of catechins in regulating diabetes: an update review

L Wen, D Wu, X Tan, M Zhong, J Xing, W Li, D Li, F Cao - Nutrients, 2022 - mdpi.com
Catechins are key functional components in tea and have many health benefits, including
relieving diabetes. Glucose is necessary for maintaining life. However, when the glucose in …

Gut microbiota induces DNA methylation via SCFAs predisposing obesity-prone individuals to diabetes

W Guo, Z Zhang, L Li, X Liang, Y Wu, X Wang… - Pharmacological …, 2022 - Elsevier
Obesity-prone (OP) individuals have a significant predisposition to obesity and diabetes.
Previously, we have found that OP individuals, despite being normal in weight and BMI …

[HTML][HTML] Gut microbiota-derived metabolites as key actors in type 2 diabetes mellitus

L Du, Q Li, H Yi, T Kuang, Y Tang, G Fan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Type 2 diabetes mellitus (T2DM) is one of the most risk factors threatening human health.
Although genetic and environmental factors contribute to the development of T2DM, gut …