Cardiovascular risk and testosterone–from subclinical atherosclerosis to lipoprotein function to heart failure
B Gencer, M Bonomi, MP Adorni, CR Sirtori… - Reviews in Endocrine …, 2021 - Springer
The cardiovascular (CV) benefit and safety of treating low testosterone conditions is a matter
of debate. Although testosterone deficiency has been linked to a rise in major adverse CV …
of debate. Although testosterone deficiency has been linked to a rise in major adverse CV …
Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis
J Hudson, M Cruickshank, R Quinton… - The Lancet Healthy …, 2022 - thelancet.com
Background Testosterone is the standard treatment for male hypogonadism, but there is
uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide …
uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide …
Androgen therapy in neurodegenerative diseases
VE Bianchi, L Rizzi, E Bresciani… - Journal of the …, 2020 - academic.oup.com
Neurodegenerative diseases, including Alzheimer disease (AD), Parkinson disease (PD),
multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and Huntington disease, are …
multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and Huntington disease, are …
Impact of biological sex and sex hormones on molecular signatures of skeletal muscle at rest and in response to distinct exercise training modes
Substantial divergence in cardio-metabolic risk, muscle size, and performance exists
between men and women. Considering the pivotal role of skeletal muscle in human …
between men and women. Considering the pivotal role of skeletal muscle in human …
Current pharmacologic treatment of dementia: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians
A Qaseem, V Snow, JT Cross Jr… - Annals of internal …, 2008 - acpjournals.org
Description: The American College of Physicians and American Academy of Family
Physicians developed this guideline to present the available evidence on current …
Physicians developed this guideline to present the available evidence on current …
Associations of serum testosterone and sex hormone–binding globulin with incident cardiovascular events in middle-aged to older men
BB Yeap, RJ Marriott, L Antonio, S Raj… - Annals of internal …, 2022 - acpjournals.org
Background: The influence of testosterone on risk for cardiovascular events in men is
uncertain. Previous observational studies of sex hormones and incident cardiovascular …
uncertain. Previous observational studies of sex hormones and incident cardiovascular …
Testosterone treatment in adult men with age-related low testosterone: a clinical guideline from the American College of Physicians
A Qaseem, CA Horwitch, S Vijan… - Annals of internal …, 2020 - acpjournals.org
Description: The American College of Physicians (ACP) developed this guideline to provide
clinical recommendations based on the current evidence of the benefits and harms of …
clinical recommendations based on the current evidence of the benefits and harms of …
[HTML][HTML] Obesity, body composition, and sex hormones: implications for cardiovascular risk
Cardiovascular disease (CVD) continues to be the leading cause of death in adults,
highlighting the need to develop novel strategies to mitigate cardiovascular risk. The …
highlighting the need to develop novel strategies to mitigate cardiovascular risk. The …
Approach to the patient: the evaluation and management of men≥ 50 years with low Serum testosterone concentration
M Grossmann, CN Jayasena… - The Journal of Clinical …, 2023 - academic.oup.com
Although testosterone replacement in men with classic hypogonadism due to an identified
pathology of the hypothalamic-pituitary-testicular axis is uncontroversial, the role of …
pathology of the hypothalamic-pituitary-testicular axis is uncontroversial, the role of …
Testosterone replacement therapy and the risk of venous thromboembolism: a systematic review and meta-analysis of randomized controlled trials
Introduction The cardiovascular safety of testosterone replacement therapy (TRT) is
controversial. While several studies have investigated the association between TRT and the …
controversial. While several studies have investigated the association between TRT and the …