Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …

Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty
deposits in the inner walls of vessels. These plaques restrict blood flow and lead to …

Atherosclerotic plaque rupture is a significant cause of acute cardiovascular events such as
heart attack and stroke, triggered by the decomposition of fiber caps induced by cysteine …

Macrophages play a central role in the development of atherosclerotic cardiovascular
disease (ASCVD), which encompasses coronary artery disease, peripheral artery disease …

Obesity is the most common cause of insulin resistance, and the current obesity epidemic is
driving a parallel rise in the incidence of T2DM. It is now widely recognized that chronic …

Atherosclerosis is considered one of the primary causes of cardiovascular diseases (CVDs).
Unpredictable rupture of the vulnerable atherosclerotic plaques triggers adverse …

Inflammatory bowel disease (IBD), comprised of ulcerative colitis and Crohn's disease, is a
chronic relapsing inflammatory disease of the gastrointestinal tract that closely related to …

Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …

Macrophages (Mφ) are primary innate immune cells that exhibit diverse functions in
response to different pathogens or stimuli, and they are extensively involved in the …