m6A-Atlas v2.0: updated resources for unraveling the N6-methyladenosine (m6A) epitranscriptome among multiple species

Z Liang, H Ye, J Ma, Z Wei, Y Wang… - Nucleic Acids …, 2024 - academic.oup.com
Abstract N 6-Methyladenosine (m6A) is one of the most abundant internal chemical
modifications on eukaryote mRNA and is involved in numerous essential molecular …

Dynamic regulation and key roles of ribonucleic acid methylation

J Zou, H Liu, W Tan, Y Chen, J Dong, S Bai… - Frontiers in Cellular …, 2022 - frontiersin.org
Ribonucleic acid (RNA) methylation is the most abundant modification in biological systems,
accounting for 60% of all RNA modifications, and affects multiple aspects of RNA (including …

RNA epigenetics in chronic lung diseases

X Wang, Z Guo, F Yan - Genes, 2022 - mdpi.com
Chronic lung diseases are highly prevalent worldwide and cause significant mortality. Lung
cancer is the end stage of many chronic lung diseases. RNA epigenetics can dynamically …

Multi-task adaptive pooling enabled synergetic learning of RNA modification across tissue, type and species from low-resolution epitranscriptomes

Y Song, Y Wang, X Wang, D Huang… - Briefings in …, 2023 - academic.oup.com
Post-and co-transcriptional RNA modifications are found to play various roles in regulating
essential biological processes at all stages of RNA life. Precise identification of RNA …

Neutrophil extracellular trap-associated risk index for predicting outcomes and response to Wnt signaling inhibitors in triple-negative breast cancer

Z Huang, J Wang, B Sun, M Qi, S Gao, H Liu - Scientific Reports, 2024 - nature.com
Triple-negative breast cancer (TNBC) is a type of breast cancer with poor prognosis, which
is prone to distant metastasis and therapy resistance. The presence of neutrophil …

m5U-GEPred: prediction of RNA 5-methyluridine sites based on sequence-derived and graph embedding features

Z Xu, X Wang, J Meng, L Zhang, B Song - Frontiers in Microbiology, 2023 - frontiersin.org
5-Methyluridine (m5U) is one of the most common post-transcriptional RNA modifications,
which is involved in a variety of important biological processes and disease development …

Analyses of m6A regulatory genes and subtype classification in atrial fibrillation

Y Zhao, Y Che, Q Liu, S Zhou, Y Xiao - Frontiers in cellular …, 2023 - frontiersin.org
Objective To explore the role of m6A regulatory genes in atrial fibrillation (AF), we classified
atrial fibrillation patients into subtypes by two genotyping methods associated with m6A …

Self-attention enabled deep learning of dihydrouridine (D) modification on mRNAs unveiled a distinct sequence signature from tRNAs

Y Wang, X Wang, X Cui, J Meng, R Rong - Molecular Therapy-Nucleic …, 2023 - cell.com
Dihydrouridine (D) is a modified pyrimidine nucleotide universally found in viral, prokaryotic,
and eukaryotic species. It serves as a metabolic modulator for various pathological …

A novel prognostic signature based on N7-methylguanosine-related long non-coding RNAs in breast cancer

Z Huang, K Lou, H Liu - Frontiers in Genetics, 2022 - frontiersin.org
Long non-coding RNA (lncRNA) are closely associated with the occurrence and progression
of tumors. However, research on N7-methylguanosine (m7G)-related lncRNA in breast …

Modification and expression of mRNA m6A in the lateral habenular of rats after long-term exposure to blue light during the sleep period

Y Li, J Ren, Z Zhang, Y Weng, J Zhang, X Zou, S Wu… - Genes, 2023 - mdpi.com
Artificial lighting, especially blue light, is becoming a public-health risk. Excessive exposure
to blue light at night has been reported to be associated with brain diseases. However, the …