The tryptophan catabolite or kynurenine pathway in COVID-19 and critical COVID-19: a systematic review and meta-analysis

AF Almulla, T Supasitthumrong… - BMC Infectious …, 2022 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) is accompanied by activated
immune-inflammatory pathways and oxidative stress, which both induce indoleamine-2, 3 …

COVID-19-associated candidiasis: possible patho-mechanism, predisposing factors, and prevention strategies

N Ahmed, MS Mahmood, MA Ullah, Y Araf… - Current …, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is threatening public health. A large number of …

Potential adverse effects of dexamethasone therapy on COVID-19 patients: review and recommendations

F Chen, L Hao, S Zhu, X Yang, W Shi, K Zheng… - Infectious diseases and …, 2021 - Springer
In the context of the coronavirus disease 2019 (COVID-19) pandemic, the global healthcare
community has raced to find effective therapeutic agents against severe acute respiratory …

What do we need to know about musculoskeletal manifestations of COVID-19?: A systematic review

RE Pires, IGN Reis, GS Waldolato, DD Pires… - JBJS …, 2022 - journals.lww.com
What Do We Need to Know About Musculoskeletal Manifestations... : JBJS Reviews What Do
We Need to Know About Musculoskeletal Manifestations of COVID-19?: A Systematic Review …

The SARS-CoV-2 S1 spike protein promotes MAPK and NF-kB activation in human lung cells and inflammatory cytokine production in human lung and intestinal …

CB Forsyth, L Zhang, A Bhushan, B Swanson, L Zhang… - Microorganisms, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic began in January 2020 in Wuhan,
China, with a new coronavirus designated SARS-CoV-2. The principal cause of death from …

Problems of pathogenesis and pathogenetic therapy of COVID-19 from the perspective of the general theory of pathological systems (general pathological processes)

E Gusev, A Sarapultsev, D Hu… - International journal of …, 2021 - mdpi.com
The COVID-19 pandemic examines not only the state of actual health care but also the state
of fundamental medicine in various countries. Pro-inflammatory processes extend far …

Macrophages: Shapes and functions

U Lendeckel, S Venz, C Wolke - ChemTexts, 2022 - Springer
Macrophages are cells of the innate immune system and represent an important component
of the first-line defense against pathogens and tumor cells. Here, their diverse functions in …

Increased kynurenine indicates a fatal course of COVID-19

H Mangge, M Herrmann, A Meinitzer, S Pailer, P Curcic… - Antioxidants, 2021 - mdpi.com
(1) Background: An inefficient immune response accompanied by an overwhelming
inflammatory reaction is involved in severe courses of COVID-19. Kynurenine (KYN) has …

Innate and adaptive immunity to SARS-CoV-2 and predisposing factors

J Shen, J Fan, Y Zhao, D Jiang, Z Niu, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus (SARS-CoV-2), has affected all countries worldwide. Although some …

Upregulation of type 1 conventional dendritic cells implicates antigen cross-presentation in multisystem inflammatory syndrome

JJ Huang, SB Gaines, ML Amezcua, TR Lubell… - Journal of Allergy and …, 2022 - Elsevier
Background Multisystem inflammatory syndrome in children (MIS-C) is an acute, febrile,
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated syndrome …