Tumor markers in colorectal cancer, gastric cancer and gastrointestinal stromal cancers: European group on tumor markers 2014 guidelines update

MJ Duffy, R Lamerz, C Haglund… - … journal of cancer, 2014 - Wiley Online Library
Biomarkers currently play an important role in the detection and management of patients
with several different types of gastrointestinal cancer, especially colorectal, gastric, gastro …

[HTML][HTML] Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy

I Riquelme, K Saavedra, JA Espinoza, H Weber… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the third leading cause of cancer mortality worldwide. Although
surgical resection is a potentially curative approach for localized cases of GC, most cases of …

Circulating microRNAs as potential diagnostic biomarkers and therapeutic targets in gastric cancer: current status and future perspectives

H Mirzaei, S Khataminfar… - Current medicinal …, 2016 - ingentaconnect.com
Gastric cancer is among the leading causes of cancer related death worldwide. Patients with
gastric cancer are typically asymptomatic, and diagnosed at late stages, supporting the need …

CHPF promotes gastric cancer tumorigenesis through the activation of E2F1

X Lin, T Han, Q Xia, J Cui, M Zhuo, Y Liang, W Su… - Cell Death & …, 2021 - nature.com
Chondroitin polymerizing factor (CHPF) is an important glycosyltransferase involved in the
biosynthesis of chondroitin sulfate. However, the relationship between CHPF and gastric …

[HTML][HTML] Rho/ROCK signaling in motility and metastasis of gastric cancer

T Matsuoka, M Yashiro - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Gastric cancer is one of the most frequent and lethal malignancies worldwide because of
high frequency of metastasis. Tumor cell motility and invasion play fundamental roles in …

Blockade of ITGA2 induces apoptosis and inhibits cell migration in gastric cancer

YC Chuang, HY Wu, YL Lin, SC Tzou… - Biological procedures …, 2018 - Springer
Background Gastric cancer is currently the fourth leading cause of cancer-related death
worldwide. Gastric cancer is often diagnosed at advanced stages and the outcome of the …

Towards sustained silencing of HER2/neu in cancer by epigenetic editing

F Falahi, C Huisman, HG Kazemier… - Molecular Cancer …, 2013 - AACR
The human epidermal growth factor receptor-2 (HER2/neu/ERBB2) is overexpressed in
several cancer types. Although therapies targeting the HER2/neu protein result in inhibition …

Bridging genomics and phenomics of gastric carcinoma

J Cho, S Ahn, DS Son, NKD Kim… - … journal of cancer, 2019 - Wiley Online Library
Genetic alterations are the starting point leading to numerous changes in clinical and
pathologic features (phenotypes) of individual cancers; however, their inter‐relationships in …

[HTML][HTML] HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development

SP Hack, JM Bruey, H Koeppen - Oncotarget, 2014 - ncbi.nlm.nih.gov
Aberrant activation of the HGF/MET signaling axis has been strongly implicated in the
malignant transformation and progression of gastroesophageal cancer (GEC). MET receptor …

Integrins αvβ3 and αvβ5 as prognostic, diagnostic, and therapeutic targets in gastric cancer

C Böger, VS Warneke, HM Behrens, H Kalthoff… - Gastric cancer, 2015 - Springer
Background We investigated the expression of two α v integrins, α v β 3 and α v β 5, in
gastric cancer (GC) by testing the following hypotheses: that these molecules are expressed …