Ferroptosis-Regulated Natural Products and miRNAs and Their Potential Targeting to Ferroptosis and Exosome Biogenesis

YT Chuang, CY Yen, TM Chien, FR Chang… - International Journal of …, 2024 - mdpi.com
Ferroptosis, which comprises iron-dependent cell death, is crucial in cancer and non-cancer
treatments. Exosomes, the extracellular vesicles, may deliver biomolecules to regulate …

NEDD4L in human tumors: regulatory mechanisms and dual effects on anti-tumor and pro-tumor

M Zhang, Z Zhang, X Tian, E Zhang, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Tumorigenesis and tumor development are closely related to the abnormal regulation of
ubiquitination. Neural precursor cell expressed developmentally downregulated 4-like …

[HTML][HTML] Identification of a PANoptosis-related gene signature for predicting the prognosis, tumor microenvironment and therapy response in breast cancer

T Yu, W Cheng, J Zhang, T Wang, Y Liu, Y Duan… - Journal of …, 2024 - ncbi.nlm.nih.gov
Breast cancer (BC) is the most prevalent malignancy among women worldwide. Mounting
evidence suggests that PANoptosis participates in cancer development and therapy …

P4HA2-induced prolyl hydroxylation of YAP1 restricts vascular smooth muscle cell proliferation and neointima formation

L Wang, T Liu, Y Zheng, J Zhou, H Hua, L Kong… - Life Sciences, 2023 - Elsevier
Vascular smooth muscle cell (VSMC) proliferation and neointima formation play significant
roles in atherosclerosis development and restenosis following percutaneous coronary …

Epigallocatechin gallate alleviates mono-2-ethylhexyl phthalate-induced male germ cell pyroptosis by inhibiting the ROS/mTOR/NLRP3 pathway

Y Hong, X Zhou, Q Li, J Chen, Y Wei, L Shen, C Long… - Toxicology in Vitro, 2023 - Elsevier
Abstract Mono-2-ethylhexyl phthalate (MEHP) exposure is known to induce severe testicular
injury via reactive oxygen species (ROS). However, few effective treatments are available for …

Autophagy Dysfunction: The Kernel of Hair Loss?

X Jin, X Song - Clinical, Cosmetic and Investigational Dermatology, 2024 - Taylor & Francis
Autophagy is recognized as a crucial regulatory process, instrumental in the removal of
senescent, dysfunctional, and damaged cells. Within the autophagic process, lysosomal …

[HTML][HTML] Role of natural products in tumor therapy from basic research and clinical perspectives

Z Wang, Z Liu, J Qu, Y Sun, W Zhou - Acta Materia Medica, 2024 - scienceopen.com
Cancer is the leading cause of morbidity and mortality worldwide and is an important barrier
to lengthening life expectancy in every country. Natural products are receiving increased …

[引用][C] Single-cell RNA sequencing reveals the effects of hederasaponin C in the treatment of diabetic nephropathy

J Liu, Q Zhang, W Zhao, J Guo, YK Wong… - Acta Materia …, 2023 - Compuscript