Copper is a vital mineral, and an optimal amount of copper is required to support normal
physiologic processes in various systems, including the cardiovascular system. Over the …

Wilson's disease (WD) is a rare autosomal recessive disorder of hepatocellular copper
deposition. The diagnostic approach to patients with WD may be challenging and is based …

Wilson's disease (WD) is characterised by a deleterious accumulation of copper in the liver
and brain. It is one of those rare genetic disorders that benefits from effective and lifelong …

In Wilson disease (WD), functional loss of ATPase copper-transporting β (ATP7B) impairs
biliary copper excretion, leading to excessive copper accumulation in the liver and fulminant …

Background & Aims Wilson's disease (WD) is an autosomal recessively inherited copper
storage disorder due to mutations in the ATP7B gene that causes hepatic and neurologic …

Objective To evaluate the effect of liver transplantation (LT) in patients with Wilson disease
(WD) with severe neurologic worsening resistant to active chelation. Methods French …

Wilson's disease (WD) is a genetic metabolic disease strictly associated with liver cirrhosis.
In this review, the genetic bases of the disease are discussed, with emphasis on the role of …

Abstract Background In Wilson's disease (WD), early neurological deterioration after
treatment initiation is associated with poor outcomes; however, data on this phenomenon …

Background Clinical scales and neuroimaging are used to monitor nervous system injury in
Wilson's disease, while data on serum markers are scarce. Objective To investigate whether …

Wilson's disease (WD) is a rare inherited disorder of copper metabolism causing toxic
hepatic and neural copper accumulation. Clinical symptoms vary widely, from asymptomatic …